Anti-BCL10 Polyclonal Antibody

Catalog No.

PHB82401

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human BCL10 (Met1-Gln233).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CED-3/ICH-1 prodomain homologous E10-like regulator, CLAP, B-cell CLL/lymphoma 10, BCL10, CARD-containing molecule enhancing NF-kappa-B, Cellular homolog of vCARMEN, cCARMEN, CIPER, Bcl-10, hCLAP, Cellular-E10, CARD-like apoptotic protein, c-E10, Mammalian CARD-containing adapter molecule E10, B-cell lymphoma/leukemia 10, mE10

Purification

Purified by antigen affinity column.

Accession

O95999

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Clinical relevance of molecular aspects in extranodal marginal zone lymphoma: a critical appraisal., PMID:37389189

Primary Cutaneous Follicle Center Lymphoma of the Eyelid in a Young Man., PMID:37338339

Benzene induces spleen injury through the B cell receptor signaling pathway., PMID:37080132

Phosphorylation of serine-893 in CARD11 suppresses the formation and activity of the CARD11-BCL10-MALT1 complex in T and B cells., PMID:35230873

Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency., PMID:33872653

Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway., PMID:33329596

B-Cell Activating Factor Enhances Hepatocyte-Driven Angiogenesis via B-Cell CLL/Lymphoma 10/Nuclear Factor-KappaB Signaling during Liver Regeneration., PMID:31658764

MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells., PMID:31644910

Gastric mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) with pancreatic acinar differentiation: a case report., PMID:31077220

Axotomy-Induced Changes of the Protein Profile in the Crayfish Ventral Cord Ganglia., PMID:31066008

Primary extranodal diffuse large B-cell lymphomas: Many sites, many entities? Clinico-pathological, immunohistochemical and cytogenetic study of 106 cases., PMID:30553470

Ubiquitination and phosphorylation of the CARD11-BCL10-MALT1 signalosome in T cells., PMID:30514565

Simulation of the Dynamics of Primary Immunodeficiencies in B Cells., PMID:30116248

Autocleavage of the paracaspase MALT1 at Arg-781 attenuates NF-κB signaling and regulates the growth of activated B-cell like diffuse large B-cell lymphoma cells., PMID:29953499

A multiprotein supercomplex controlling oncogenic signalling in lymphoma., PMID:29925955

Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9., PMID:28130494

B-cell receptor-driven MALT1 activity regulates MYC signaling in mantle cell lymphoma., PMID:27864294

Profiling of Signaling Proteins in Penumbra After Focal Photothrombotic Infarct in the Rat Brain Cortex., PMID:27771897

MALT lymphoma: A paradigm of NF-κB dysregulation., PMID:27452667

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma., PMID:27070702

Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo., PMID:27032818

Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity., PMID:26936881

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling., PMID:26525107

Concomitant high expression of Toll-like receptor (TLR) and B-cell receptor (BCR) signalling molecules has clinical implications in mantle cell lymphoma., PMID:26354285

IgG4-positive extranodal marginal zone lymphoma arising in Hashimoto's thyroiditis: clinicopathological and cytogenetic features of a hitherto undescribed condition., PMID:26332259

Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation., PMID:26038114

Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation., PMID:25627829

E-cadherin-negative acinar cell carcinoma of the pancreas: report of a case showing a solid pseudopapillary growth pattern., PMID:25600280

Differential expression of Toll-like receptor (TLR) and B cell receptor (BCR) signaling molecules in primary diffuse large B-cell lymphoma of the central nervous system., PMID:25391967

Inhibiting CARD11 translation during BCR activation by targeting the eIF4A RNA helicase., PMID:25320244

C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation., PMID:25202022

The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency., PMID:25087226

Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein-protein interactions in relation to subcellular localization., PMID:25011391

BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response., PMID:24732096

CARD11 blockade suppresses murine collagen-induced arthritis via inhibiting CARD11/Bcl10 assembly and T helper type 17 response., PMID:24443940

Bcl10 is an essential regulator for A20 gene expression., PMID:23677497

Lung endothelial cell apoptosis during ischemic acute kidney injury., PMID:22777112

Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased VH4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment., PMID:22382892

Delineation of apoptotic genes for synergistic apoptosis of lexatumumab and anthracyclines in human renal cell carcinoma cells by polymerase chain reaction array., PMID:22205156

CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB., PMID:21513986

CD4 ligation excludes the Carma1-Bcl10-MALT1 complex from GM1-positive membrane rafts in CD3/CD28 activated T cells., PMID:21489413

Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells., PMID:21282629

Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1., PMID:20685844

[Orbital and ocular adnexal lymphomas. Clinico-pathological correlation in 25 cases]., PMID:20679053

Expression of CARD6, an NF-kappaB activator, in gastric, colorectal and oesophageal cancers., PMID:20025480

[Recent progress in lymphoma genomics and biology]., PMID:19915361

Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma., PMID:19696203

Antibodies to Helicobacter pylori and CagA protein are associated with the response to antibacterial therapy in patients with H. pylori-positive API2-MALT1-negative gastric MALT lymphoma., PMID:19385974

CARD9 versus CARMA1 in innate and adaptive immunity., PMID:19359218

Nuclear BCL10 in primary Sjögren's syndrome., PMID:19298243

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