Catalog No.
PHK02001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human BCL11A (Met1-Arg210).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
B-cell CLL/lymphoma 11A, EVI-9, CTIP1, EVI9, Zinc finger protein 856, KIAA1809, B-cell lymphoma/leukemia 11A, COUP-TF-interacting protein 1, Ecotropic viral integration site 9 protein homolog, ZNF856, BCL11A, BCL-11A
Purification
Purified by antigen affinity column.
Accession
Q9H165
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate., PMID:39642886
Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation., PMID:37273902
Evolution of nanobodies specific for BCL11A., PMID:36626555
β-Thalassemia: evolving treatment options beyond transfusion and iron chelation., PMID:34889443
An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production., PMID:28851297
Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease., PMID:27393735
Multicolor staining of globin subtypes reveals impaired globin switching during erythropoiesis in human pluripotent stem cells., PMID:24873860
Decreased miR-146 expression in peripheral blood mononuclear cells is correlated with ongoing islet autoimmunity in type 1 diabetes patients 1miR-146., PMID:24796653
Global mitotic phosphorylation of C2H2 zinc finger protein linker peptides., PMID:21941085
Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells., PMID:21255732
X-linked mental retardation gene CASK interacts with Bcl11A/CTIP1 and regulates axon branching and outgrowth., PMID:20623620
Chronic lymphocytic leukemia With t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated with atypical morphologic features and unmutated IgVH genes., PMID:19369625
BCL2 and BCL3 are recurrent translocation partners of the IGH locus., PMID:18940474
BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body., PMID:18681895
Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosis., PMID:18547320
Chronic lymphocytic leukemia FISH panel: impact on diagnosis., PMID:17638669
Expression of zinc finger transcription factor Bcl11A/Evi9/CTIP1 in rat brain., PMID:17455301
Rapid amplification of immunoglobulin heavy chain switch (IGHS) translocation breakpoints using long-distance inverse PCR., PMID:15496980
The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia., PMID:12040429
Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene., PMID:11986957
The BCL11 gene family: involvement of BCL11A in lymphoid malignancies., PMID:11719382
Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product., PMID:10757802
For research use only. Not for human or drug use.
