Catalog No.
PHJ77901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MBD1 (Met1-Leu216).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CXXC3, PCM1, CXXC-type zinc finger protein 3, Protein containing methyl-CpG-binding domain 1, Methyl-CpG-binding domain protein 1, MBD1, Methyl-CpG-binding protein MBD1
Purification
Purified by antigen affinity column.
Accession
Q9UIS9
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis., PMID:36574452
Thymoquinone upregulates IL17RD in controlling the growth and metastasis of triple negative breast cancer cells in vitro., PMID:35761256
Melatonin-induced suppression of DNA methylation promotes odontogenic differentiation in human dental pulp cells., PMID:32718272
β-Defensins Coordinate In Vivo to Inhibit Bacterial Infections of the Trachea., PMID:30154362
Human β-defensin-3 induces IL-8 release and apoptosis in airway smooth muscle cells., PMID:28437599
The effect of DNA damage on the pattern of immune-detectable DNA methylation in mouse embryonic fibroblasts., PMID:26410557
A new strategy for methylated DNA detection based on photoelectrochemical immunosensor using Bi2S3 nanorods, methyl bonding domain protein and anti-his tag antibody., PMID:23948240
Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cells., PMID:23441133
Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation., PMID:22945648
Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14., PMID:20944649
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias., PMID:20818161
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications., PMID:20565761
DNA methylation profiling using live-cell imaging., PMID:20412856
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine., PMID:20371518
Visualization of DNA methylation and histone modifications in living cells., PMID:20207127
Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells., PMID:19856314
Overexpression of RFT induces G1-S arrest and apoptosis via p53/p21(Waf1) pathway in glioma cell., PMID:15081425
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression., PMID:14610093
Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns., PMID:14519686
Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma., PMID:11823513
Active repression of methylated genes by the chromosomal protein MBD1., PMID:10648624
A methylation-responsive MDBP/RFX site is in the first exon of the collagen alpha2(I) promoter., PMID:10593968
For research use only. Not for human or drug use.
