Catalog No.
PHD44101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD247/CD3Z (Arg52-Arg164).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CD3Z, CD247, TCRZ, T-cell receptor T3 zeta chain, T3Z, T-cell surface glycoprotein CD3 zeta chain
Purification
Purified by antigen affinity column.
Accession
P20963
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures., PMID:39462122
Effects of immunorelated gene polymorphisms on trastuzumab targeting breast cancer cell in vitro., PMID:39392082
Nonsense CD247 mutations show dominant-negative features in T-cell receptor expression and function., PMID:38992472
Identification of a Fully Human Antibody VH Domain Targeting Anaplastic Lymphoma Kinase (ALK) with Applications in ALK-Positive Solid Tumor Immunotherapy., PMID:38804307
Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis., PMID:37868834
Advances in the study of CD47-based bispecific antibody in cancer immunotherapy., PMID:35575882
Human Cytomegalovirus Infection Promotes Expansion of a Functionally Superior Cytoplasmic CD3+ NK Cell Subset with a Bcl11b-Regulated T Cell Signature., PMID:34625521
CAR T-cell therapy for multiple myeloma: state of the art and prospects., PMID:34048683
The Role of CD247 Polymorphisms in Bulgarian Patients with Systemic Lupus Erythematosus., PMID:30064597
Effects of immuno-related gene polymorphisms on a bispecific antibody targeting colorectal cancer cell., PMID:29790821
Clinical Significance of Circulating CD33+CD11b+HLA-DR- Myeloid Cells in Patients with Stage IV Melanoma Treated with Ipilimumab., PMID:27178742
TCR-CD3ζ gene polymorphisms and expression profile in rheumatoid arthritis., PMID:27118209
Effect of induction therapy on the expression of molecular markers associated with rejection and tolerance., PMID:26286066
Expression pattern of T-helper 17 cell signaling pathway and mucosal inflammation in celiac disease., PMID:24325470
Down regulation of T cell receptor expression in COPD pulmonary CD8 cells., PMID:23977094
IRF5 polymorphism predicts prognosis in patients with systemic sclerosis., PMID:22440820
Association of CD247 with systemic lupus erythematosus in Asian populations., PMID:22004975
Using gene co-expression network analysis to predict biomarkers for chronic lymphocytic leukemia., PMID:21044363
Interleukin-21 can efficiently restore impaired antibody-dependent cell-mediated cytotoxicity in patients with oesophageal squamous cell carcinoma., PMID:20029417
Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2., PMID:18089830
Profiling lymphocyte subpopulations in peripheral blood under efalizumab treatment of psoriasis by multi epitope ligand cartography (MELC) robot microscopy., PMID:17229602
For research use only. Not for human or drug use.
