Anti-Human IDO2/INDOL1 Polyclonal Antibody

Catalog No.

PHK28101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IDO2/INDOL1 (Met14-Gly420).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

INDOL1, Indoleamine 2,3-dioxygenase-like protein 1, IDO2, IDO-2, Indoleamine-pyrrole 2,3-dioxygenase-like protein 1, Indoleamine 2,3-dioxygenase 2

Purification

Purified by antigen affinity column.

Accession

Q6ZQW0

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Epacadostat Overcomes Cetuximab Resistance in Colorectal Cancer by Targeting IDO-Mediated Tryptophan Metabolism., PMID:40103010

Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment., PMID:37345056

The role of indoleamine 2,3-dioxygenase 1 in early-onset post-stroke depression., PMID:36911716

Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS)., PMID:36389710

A novel 10-gene immune-related lncRNA signature model for the prognosis of colorectal cancer., PMID:34814366

Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses., PMID:32973768

B-Cell-Targeted 3DNA Nanotherapy Against Indoleamine 2,3-Dioxygenase 2 (IDO2) Ameliorates Autoimmune Arthritis in a Preclinical Model., PMID:32924009

HIV-1 Tat - TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway., PMID:32424165

Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells., PMID:32384638

IDO Targeting in Sarcoma: Biological and Clinical Implications., PMID:32194552

Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice., PMID:31555267

Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond., PMID:30203227

Therapeutic antibody targeting of indoleamine-2,3-dioxygenase (IDO2) inhibits autoimmune arthritis., PMID:28223071

IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis., PMID:24489090

The JAK inhibitor, tofacitinib, reduces the T cell stimulatory capacity of human monocyte-derived dendritic cells., PMID:24013646

Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway., PMID:23798565

Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis., PMID:20181893

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