Catalog No.
PHF81201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TFAM (Ser43-Cys246).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Transcription factor 6-like 2, Mitochondrial transcription factor 1, MtTF1, mtTFA, Transcription factor 6, TCF6, TCF6L2, Transcription factor A, mitochondrial, TCF-6, TFAM
Purification
Purified by antigen affinity column.
Accession
Q00059
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Anti-TFAM antibodies link mitochondrial damage with antiphospholipid syndrome and thrombosis in SLE., PMID:40350373
Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters., PMID:40027624
Application of Flow Cytometric Analysis for Measuring Multiple Mitochondrial Parameters in 3D Brain Organoids., PMID:37590511
Parkinson's disease neurons exhibit alterations in mitochondrial quality control proteins., PMID:37553379
Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis., PMID:37516222
Possible frequent multiple mitochondrial DNA copies in a single nucleoid in HeLa cells., PMID:37031254
Flow Cytometric Analysis of Multiple Mitochondrial Parameters in Human Induced Pluripotent Stem Cells and Their Neural and Glial Derivatives., PMID:34806709
Rescue of thyroid cells from antibody induced cell death via induction of autophagy., PMID:34801870
Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury., PMID:33997750
Proteome Analysis Reveals Distinct Mitochondrial Functions Linked to Interferon Response Patterns in Activated CD4+ and CD8+ T Cells., PMID:31354474
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men., PMID:30873124
Neuroprotective effects of topical coenzyme Q10 + vitamin E in mechanic optic nerve injury model., PMID:30852912
CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth., PMID:30289973
Role of l-carnitine and oleate in myogenic differentiation: implications for myofiber regeneration., PMID:30149425
TFAM is a novel mediator of immunogenic cancer cell death., PMID:29872558
3D super-resolution microscopy reflects mitochondrial cristae alternations and mtDNA nucleoid size and distribution., PMID:29727614
Pattern recognition receptors mediate pro-inflammatory effects of extracellular mitochondrial transcription factor A (TFAM)., PMID:29678518
Prognostic Significance of Mitochondrial Transcription Factor A Expression in Patients with Right- or Left-sided Colorectal Cancer., PMID:29277826
Mitochondrial transcription factor A (TFAM) is upregulated in glioma., PMID:28440425
Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production., PMID:27280778
Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus., PMID:27091841
The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury., PMID:26535995
Coupled aggregation of mitochondrial single-strand DNA-binding protein tagged with Eos fluorescent protein visualizes synchronized activity of mitochondrial nucleoids., PMID:26239383
BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension., PMID:25863249
Correlative light and electron microscopic observation of mitochondrial DNA in mammalian cells by using focused-ion beam scanning electron microscopy., PMID:25359841
Increased 8-hydroxy-2'-deoxyguanosine in plasma and decreased mRNA expression of human 8-oxoguanine DNA glycosylase 1, anti-oxidant enzymes, mitochondrial biogenesis-related proteins and glycolytic enzymes in leucocytes in patients with systemic lupus erythematosus., PMID:24345202
Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells., PMID:23172368
Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3β and p53 in response to tumor necrosis factor α., PMID:22911714
Mitochondrial transcription factor A is a proinflammatory mediator in hemorrhagic shock., PMID:22469910
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA., PMID:21808029
CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation., PMID:18227154
Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane., PMID:16825194
PDIP38 associates with proteins constituting the mitochondrial DNA nucleoid., PMID:16428295
Human mitochondrial DNA is packaged with TFAM., PMID:12626705
DNA-activated ATPase activity associated with Xenopus transcription factor A., PMID:2943735
For research use only. Not for human or drug use.
