Catalog No.
PHK00301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DPYSL5 (Met1-Ala205).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Collapsin response mediator protein 5, CRAM, CRMP-5, Dihydropyrimidinase-related protein 5, ULIP-6, UNC33-like phosphoprotein 6, CRMP5, ULIP6, DPYSL5, DRP-5, CRMP3-associated molecule
Purification
Purified by antigen affinity column.
Accession
Q9BPU6
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Late-onset Chorea with a Rare but Identifiable Cause., PMID:38881119
Cortical laminar necrosis due to hypoglycemia in anti-CV2/CRMP5 paraneoplastic encephalitis: a curious association., PMID:38563874
Small cell carcinoma presenting as ocular paraneoplastic syndrome due to CRMP-5., PMID:33459291
CRMP-5-IgG Antibody: role in the bilateral uveitis with swollen disc., PMID:32685790
[A case of paraneoplastic myelopathy associated with anti-CV2/CRMP5 antibodies with small-cell lung cancer]., PMID:32641628
Anti-CV2/CRMP5 antibody-associated hemorrhagic leukoencephalomyelitis treated with steroids, intravenous immunoglobulin, plasmapheresis, and cyclophosphamide., PMID:32044694
Rare case: paraneoplastic syndrome affecting peripheral nerves, associated with anti-collapsin-response mediator protein-5 (anti-CRMP5) antibodies, as early manifestation of small cell lung cancer confined to a solitary lymph node without evidence of lung mass on routine CT thorax., PMID:32033998
Limbic encephalitis associated with AMPA receptor and CRMP5 antibodies: A case report and literature review., PMID:31991060
Collapsin Response-Mediator Protein 5-Associated Retinitis, Vitritis, and Optic Disc Edema., PMID:31676123
Anti-CV2/CRMP5 Paraneoplastic Chorea Effectively Managed with Intravenous Amantadine., PMID:31656691
Amphiphysin-IgG autoimmune neuropathy: A recognizable clinicopathologic syndrome., PMID:31624089
Detection of serum anti-retinal antibodies in the Chinese patients with presumed autoimmune retinopathy., PMID:31119427
Inflammatory flaccid myelitis in a patient with both anti-CRMP-5 IgG and CNS HIV escape., PMID:31118171
Anti-CV2-Associated Paraneoplastic Hemichorea Secondary to Diffuse Large B-cell Lymphoma., PMID:31057136
Paraneoplastic striatal encephalitis and myelitis associated with anti-CV2/CRMP-5 antibodies in a patient with small cell lung cancer., PMID:29777943
Coexistence of Lambert-Eaton myasthenic syndrome and autoimmune encephalitis with anti-CRMP5/CV2 and anti-GABAB receptor antibodies in small cell lung cancer: A case report., PMID:29742721
Autoimmune encephalitis positive for both anti-γ-aminobutyric acid B receptor and anticollapsin response-mediator protein 5 antibodies: A case report., PMID:29504979
CV2/CRMP5-antibody-related Paraneoplastic Optic Neuropathy Associated with Small-cell Lung Cancer., PMID:29321433
Paraneoplastic Optic Neuropathy and Pineal Germinoma With Collapsin Response-Mediating Protein Antibodies., PMID:29266032
Autoimmune CRMP5 neuropathy phenotype and outcome defined from 105 cases., PMID:29222126
Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology., PMID:29053777
Double trouble: para-neoplastic anti-PCA-2 and CRMP-5-mediated small fibre neuropathy followed by chorea associated with small cell lung cancer and evolving radiological features., PMID:27571910
Rapidly progressive neurological deterioration in anti-AMPA receptor encephalitis with additional CRMP5 antibodies., PMID:27465029
Anti-collapsin response mediator protein 5 encephalitis masquerading as a low-grade brain tumour., PMID:27247429
Autoimmune myelopathies., PMID:27112686
Pitfalls in the detection of CV2 (CRMP5) antibodies., PMID:26711575
Clinical and Histological Features of Small Cell Lung Cancer Paraneoplastic Inflammatory Uveitis., PMID:26173097
Paraneoplastic cerebellar degeneration with anti-CV2/CRMP5 antibodies and prostate adenocarcinoma., PMID:25686614
An 8-year old boy with continuous spikes and waves during slow sleep presenting with positive onconeuronal antibodies., PMID:25596064
Small cell lung cancer and progressive retinopathy., PMID:25422332
Paraneoplastic Hu and CRMP5 antibodies are present in smokers without cancer or neurological disease., PMID:24697843
A case of paraneoplastic optic neuropathy and outer retinitis positive for autoantibodies against collapsin response mediator protein-5, recoverin, and α-enolase., PMID:24428923
Hemichorea in a thymoma patient without anti-CRMP-5 antibody., PMID:24413817
Chorea secondary to striatal encephalitis due to anti-CV2/CRMP5 antibodies. Case description and review of the literature., PMID:24332782
Orthostatic hypotension secondary to CRMP-5 paraneoplastic autonomic neuropathy., PMID:24268757
Paraneoplastic CRMP-5 basal ganglionitis and limbic encephalitis in an elderly Indian lady., PMID:24262464
A case of severe chronic progressive axonal polyradiculoneuropathy temporally associated with anti-CV2/CRMP5 antibodies., PMID:23965404
Avidity of onconeural antibodies is of clinical relevance., PMID:23733227
Multiplex serology of paraneoplastic antineuronal antibodies., PMID:23500780
[Neurologic paraneoplastic syndrome with anti-CV2/CRMP5 antibodies revealing a small cell lung cancer. Effectiveness of the lung cancer treatment]., PMID:22387203
Antibodies to CV2/CRMP5 in neuromyelitis optica-like disease: case report and review of the literature., PMID:22138095
CRMP5 regulates generation and survival of newborn neurons in olfactory and hippocampal neurogenic areas of the adult mouse brain., PMID:21991301
Demyelinating neuropathy with anti-CRMP5 antibodies predating diagnosis of breast carcinoma: favorable outcome after cancer therapy., PMID:21484830
Axon growth and guidance genes identify nascent, immature, and mature olfactory sensory neurons., PMID:20882566
Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury., PMID:20688809
[Neuropathy associated with paraneoplastic neurological syndrome]., PMID:20420179
[Paraneoplastic retinopathy and optic neuropathy]., PMID:20420177
[Limbic encephalitis with antibodies against intracellular antigens]., PMID:20420174
Glazed (vision) and confused., PMID:19804892
Anti-CV2 associated cerebellar degeneration after complete response to chemoradiation of head and neck carcinoma., PMID:19798470