Catalog No.
PHG58601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DCTN2 (Met1-Lys401).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
p50 dynamitin, DCTN50, DCTN2, Dynactin subunit 2, DCTN-50, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit
Purification
Purified by antigen affinity column.
Accession
Q13561
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy., PMID:38773124
Neither alpha-synuclein-preformed fibrils derived from patients with GBA1 mutations nor the host murine genotype significantly influence seeding efficacy in the mouse olfactory bulb., PMID:37662402
The expression, localisation and interactome of pigeon CRY2., PMID:34645873
Recruitment of dynein to late endosomes and lysosomes through light intermediate chains., PMID:21169557
Inhibition of dynein but not kinesin induces aberrant focal accumulation of neurofilaments within axonal neurites., PMID:17640622
Role of the human T-cell leukemia virus type 1 PTAP motif in Gag targeting and particle release., PMID:16537631
Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex., PMID:15496417
Evidence for glucocorticoid receptor transport on microtubules by dynein., PMID:15485845
Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1., PMID:15304525
Chlamydia trachomatis uses host cell dynein to traffic to the microtubule-organizing center in a p50 dynamitin-independent process., PMID:12902405
Assembly of centrosomal proteins and microtubule organization depends on PCM-1., PMID:12403812
Cytoplasmic dynein/dynactin mediates the assembly of aggresomes., PMID:12211113
Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function., PMID:11889140
Identification of novel molecular components of the photoreceptor connecting cilium by immunoscreens., PMID:11846514
p53 is associated with cellular microtubules and is transported to the nucleus by dynein., PMID:11025661
Real time imaging reveals a peroxisomal reticulum in living cells., PMID:11017881
Protein kinase C-regulated dynamitin-macrophage-enriched myristoylated alanine-rice C kinase substrate interaction is involved in macrophage cell spreading., PMID:10827182
Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170., PMID:10588646
Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization., PMID:10545494
Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres., PMID:9499420
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution., PMID:9334349
For research use only. Not for human or drug use.
