Catalog No.
PHJ97901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human BHMT (Lys11-Leu314).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Betaine--homocysteine S-methyltransferase 1, BHMT
Purification
Purified by antigen affinity column.
Accession
Q93088
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Deficiency of betaine-homocysteine methyltransferase activates glucose-6-phosphate dehydrogenase (G6PD) by decreasing arginine methylation of G6PD in hepatocellular carcinogenesis., PMID:38679670
Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts., PMID:25466894
Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity., PMID:24465277
Genetic polymorphisms of the enzymes involved in DNA methylation and synthesis in elite athletes., PMID:21673074
Expression of methylation pathway enzymes in bovine oocytes and preimplantation embryos., PMID:20073048
Rat liver 10-formyltetrahydrofolate dehydrogenase, carbamoyl phosphate synthetase 1 and betaine homocysteine S-methytransferase were co-purified on Kunitz-type soybean trypsin inhibitor-coupled sepharose CL-4B., PMID:17669278
Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis., PMID:17400755
Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase., PMID:10417327
Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene., PMID:9281325