Catalog No.
PHA80301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human EDIL3 (Asp24-Glu480).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
EDIL3, Integrin-binding protein DEL1, DEL1, Developmentally-regulated endothelial cell locus 1 protein, EGF-like repeat and discoidin I-like domain-containing protein 3
Purification
Purified by antigen affinity column.
Accession
O43854
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nivolumab plus relatlimab in advanced melanoma: RELATIVITY-047 4-year update., PMID:40513285
Rationale and feasibility of a rapid integral biomarker program that informs immune-oncology clinical trials: the ADVISE trial., PMID:40389374
Protocol for in-plate staining of clinical peripheral blood mononuclear cell samples for high-throughput analysis via spectral flow cytometry., PMID:40347474
Clinico-genomic features predict distinct metastatic phenotypes in cutaneous melanoma., PMID:39975034
Cigarette Smoking and Symptom Burden: Baseline Results From Nine ECOG-ACRIN Cancer Clinical Trials., PMID:39746495
Long-term outcomes among patients who respond within the first year to nivolumab plus ipilimumab or nivolumab monotherapy: A pooled analysis in 935 patients., PMID:39612757
Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas., PMID:39554029
Targeting RAF1 gene fusions with MEK inhibition in metastatic melanoma., PMID:39504576
Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans., PMID:39345527
EDIL3 alleviates Mannan-induced psoriatic arthritis by slowing the intracellular glycolysis process in mononuclear-derived dendritic cells., PMID:39289212
Nivolumab maintenance improves overall survival of patients with advanced melanoma who experience severe immune-related adverse events on nivolumab plus ipilimumab., PMID:39209453
Immunologic signatures of response and resistance to nivolumab with ipilimumab in advanced metastatic cancer., PMID:39190534
Genetic variants associated with immune-mediated liver injury from checkpoint inhibitors., PMID:39185906
The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development., PMID:38081212
EDIL3 as an Angiogenic Target of Immune Exclusion Following Checkpoint Blockade., PMID:37728484
Presence of coronary aneurysms during Kawasaki Disease (KD) correlates with lower levels of autoantibodies to both full form and spliced variant of immune regulator Del-1., PMID:37019289
Highly sensitive fluorescent detection of EDIL3 overexpressed exosomes for the diagnosis of triple-negative breast cancer., PMID:35820407
DEL1 protects against chondrocyte apoptosis through integrin binding., PMID:30278915
Developmental endothelial locus-1 (Del-1) antagonizes Interleukin-17-mediated allergic asthma., PMID:29437247
The extracellular matrix protein Edil3 stimulates osteoblast differentiation through the integrin α5β1/ERK/Runx2 pathway., PMID:29182679
Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors., PMID:27864696
Development of a novel multiplex beads-based assay for autoantibody detection for colorectal cancer diagnosis., PMID:26915739
Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin., PMID:24352615
Immune response profiling identifies autoantibodies specific to Moyamoya patients., PMID:23518061
Developmental endothelial locus-1 (Del-1) mediates clearance of platelet microparticles by the endothelium., PMID:22388320
[Expressions of receptor tyrosine kinases mRNA and protein in carcinoma of bladder]., PMID:21906447
The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion., PMID:18090124
Expression of developmentally regulated endothelial cell locus 1 was induced by tumor-derived factors including VEGF., PMID:15964546
Biodistribution and safety studies of hDel-1 plasmid-based gene therapy in mouse and rabbit models., PMID:15005876
Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3)., PMID:11959660
For research use only. Not for human or drug use.
