Catalog No.
PHA06801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SIRPB1 (Ser127-Gly356).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SIRP-beta-1, Signal-regulatory protein beta-1, CD172 antigen-like family member B, SIRPB1, CD172b
Purification
Purified by antigen affinity column.
Accession
O00241
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
FOSL1-mediated LINC01566 negatively regulates CD4+ T-cell activation in myasthenia gravis., PMID:39113081
SIRPB1 regulates inflammatory factor expression in the glioma microenvironment via SYK: functional and bioinformatics insights., PMID:38594692
Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease., PMID:30689579
Low Percentage of Signal Regulatory Protein α/β+ Memory B Cells in Blood Predicts Development of Anti-drug Antibodies (ADA) in Adalimumab-Treated Rheumatoid Arthritis Patients., PMID:30568660
OX130 Monoclonal Antibody Recognizes Human SIRPβ1 but Cross-Reacts on SIRPα from One Allele., PMID:26871367
Nature and nurture: a case of transcending haematological pre-malignancies in a pair of monozygotic twins adding possible clues on the pathogenesis of B-cell proliferations., PMID:25752595
Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment., PMID:23826770
Signal regulatory protein-beta1: a microglial modulator of phagocytosis in Alzheimer's disease., PMID:19893026
Novel structural determinants on SIRP alpha that mediate binding to CD47., PMID:18025220
SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration., PMID:16081415
Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells., PMID:11313266
For research use only. Not for human or drug use.
