Catalog No.
PHF05601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NAGLU (Val485-Trp743).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NAGLU, Alpha-N-acetylglucosaminidase, N-acetyl-alpha-glucosaminidase, UFHSD1, NAG
Purification
Purified by antigen affinity column.
Accession
P54802
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
Safety, pharmacokinetics and CNS distribution of tralesinidase alfa administered via intracerebroventricular infusion to juvenile cynomolgus monkeys., PMID:36923444
A phase I/II study on intracerebroventricular tralesinidase alfa in patients with Sanfilippo syndrome type B., PMID:36413418
Threshold for Pre-existing Antibody Levels Limiting Transduction Efficiency of Systemic rAAV9 Gene Delivery: Relevance for Translation., PMID:31193101
Identification of an anti-sperm auto-monoclonal antibody (Ts4)-recognized molecule in the mouse sperm acrosomal region and its inhibitory effect on fertilization in vitro., PMID:27064211
Insulin Receptor Antibody-α-N-Acetylglucosaminidase Fusion Protein Penetrates the Primate Blood-Brain Barrier and Reduces Glycosoaminoglycans in Sanfilippo Type B Fibroblasts., PMID:26910785
A GLP-Compliant Toxicology and Biodistribution Study: Systemic Delivery of an rAAV9 Vector for the Treatment of Mucopolysaccharidosis IIIB., PMID:26684447
Viscosity-Lowering Effect of Amino Acids and Salts on Highly Concentrated Solutions of Two IgG1 Monoclonal Antibodies., PMID:26528726
Feasibility and safety of systemic rAAV9-hNAGLU delivery for treating mucopolysaccharidosis IIIB: toxicology, biodistribution, and immunological assessments in primates., PMID:24720466
Genetic and pathological links between Parkinson's disease and the lysosomal disorder Sanfilippo syndrome., PMID:22102531
Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B., PMID:22096577
Immunization of broiler chickens against Clostridium perfringens-induced necrotic enteritis using purified recombinant immunogenic proteins., PMID:19848081
Innate and adaptive immune activation in the brain of MPS IIIB mouse model., PMID:18951493
Wheat germ agglutinin-induced platelet activation via platelet endothelial cell adhesion molecule-1: involvement of rapid phospholipase C gamma 2 activation by Src family kinases., PMID:11669637
Expression and characterization of human recombinant and alpha-N-acetylglucosaminidase., PMID:11237686
For research use only. Not for human or drug use.
