Catalog No.
PHA99101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PLA2G6 (Asp484-Val701).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Patatin-like phospholipase domain-containing protein 9, Group VI phospholipase A2, iPLA2-beta, PLA2G6, PLPLA9, Intracellular membrane-associated calcium-independent phospholipase A2 beta, GVI PLA2, CaI-PLA2, Palmitoyl-CoA hydrolase, 2-lysophosphatidylcholine acylhydrolase, 85/88 kDa calcium-independent phospholipase A2, PNPLA9
Purification
Purified by antigen affinity column.
Accession
O60733
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Genetic Factors in Antiphospholipid Syndrome: Preliminary Experience with Whole Exome Sequencing., PMID:33333988
Porcine FcεRI Mediates Porcine Reproductive and Respiratory Syndrome Virus Multiplication and Regulates the Inflammatory Reaction., PMID:29761267
PLA2G6 accumulates in Lewy bodies in PARK14 and idiopathic Parkinson's disease., PMID:28213071
Deficiency of iPLA₂β Primes Immune Cells for Proinflammation: Potential Involvement in Age-Related Mesenteric Lymph Node Lymphoma., PMID:26690222
Asthenozoospermia and membrane remodeling enzymes: a new role for phospholipase A2., PMID:26446356
Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice., PMID:25213337
Isoforms of secretory group two phospholipase A (sPLA2) in mouse ocular surface epithelia and lacrimal glands., PMID:22467583
[Adult-onset case of idiopathic neurodegeneration with brain iron accumulation without mutations in the PANK2 and PLA2G6 genes]., PMID:19827596
Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations., PMID:18202189
Phospholipases A2 in normal human conjunctiva and from patients with primary open-angle glaucoma and exfoliation glaucoma., PMID:18196260
Gestation age-related increase in 50-kDa rat uterine calcium-independent phospholipase A2 expression influences uterine sensitivity to polychlorinated biphenyl stimulation., PMID:16436530
Fcgamma RI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cells., PMID:15007079
A novel laminin-induced LPA autocrine loop in the migration of ovarian cancer cells., PMID:12824286
I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation., PMID:12208880
Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for iPLA2beta., PMID:11278673
The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A(2)., PMID:10744668
Immunohistochemical localization and characterization of a rat Clara cell 26-kDa protein (CC26) with similarities to glutathione peroxidase and phospholipase A2., PMID:10483522
Protein kinase C and a calcium-independent phospholipase are required for IgG-mediated phagocytosis by Mono-Mac-6 cells., PMID:10380910
Cloning and expression of a group IV cytosolic Ca2+-dependent phospholipase A2 from rat pancreatic islets. Comparison of the expressed activity with that of an islet group VI cytosolic Ca2+-independent phospholipase A2., PMID:9555100
Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution., PMID:9612290
For research use only. Not for human or drug use.
