Catalog No.
PHB11501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human KDM4A (Tyr141-Lys310).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Lysine-specific demethylase 4A, JMJD2, Jumonji domain-containing protein 2A, KDM4A, KIAA0677, JHDM3A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, JMJD2A, JmjC domain-containing histone demethylation protein 3A
Purification
Purified by antigen affinity column.
Accession
O75164
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Comprehensive multiplexed autoantibody profiling of patients with advanced urothelial cancer., PMID:38309723
RETRACTED: KDM4A promotes the growth of non-small cell lung cancer by mediating the expression of Myc via DLX5 through the Wnt/β-catenin signaling pathway., PMID:33002480
RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A., PMID:32883983
Circ_SPECC1 enhances the inhibition of miR-526b on downstream KDM4A/YAP1 pathway to regulate the growth and invasion of gastric cancer cells., PMID:31349968
Novel inhibitors of lysine (K)-specific Demethylase 4A with anticancer activity., PMID:28905188
SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication., PMID:28212444
The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations., PMID:28051298
Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy., PMID:27612013
Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine., PMID:27171244
KDM4A, KDM4B and KDM4C in non-small cell lung cancer., PMID:26722485
Tetrazolylhydrazides as Selective Fragment-Like Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A., PMID:26337137
Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry., PMID:20583823
Diversity within the JMJD2 histone demethylase family., PMID:17207460
Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein., PMID:15927959
For research use only. Not for human or drug use.
