Catalog No.
PHA52901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ABCC4 (Ile1041-Gln1274).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, IF: 1:50-1:100, WB: 1:1000-1:4000
Target
MOAT-B, MOATB, Multi-specific organic anion transporter B, ATP-binding cassette sub-family C member 4, Multidrug resistance-associated protein 4, MRP4, ABCC4, MRP/cMOAT-related ABC transporter
Purification
Purified by antigen affinity column.
Accession
O15439
Applications
ELISA, IHC, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Differential Selectivity of Human and Mouse ABCC4/Abcc4 for Arsenic Metabolites., PMID:39313329
Identification of ADME genes polymorphic variants linked to trastuzumab-induced cardiotoxicity in breast cancer patients: Case series of mono-institutional experience., PMID:38547766
Anti-drug resistance, anti-inflammation, and anti-proliferation activities mediated by melatonin in doxorubicin-resistant hepatocellular carcinoma: in vitro investigations., PMID:36651944
Brief Report: Relationship Between ABCC4 SNPs and Hepatitis B Virus Suppression During Tenofovir-Containing Antiretroviral Therapy in Patients With HIV/HBV Coinfection., PMID:31335591
Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters., PMID:28493713
An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins., PMID:24121517
Down-regulation of brush border efflux transporter expression in the kidneys of pregnant mice., PMID:22896729
Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier., PMID:21990609
Changes of organic anion transporter MRP4 and related nuclear receptors in human obstructive cholestasis., PMID:21359593
ABC efflux transporters in brain vasculature of Alzheimer's subjects., PMID:20727860
Molecular characterization of cultured adult human liver progenitor cells., PMID:19874131
High resolution genome-wide analysis of chromosomal alterations in Burkitt's lymphoma., PMID:19759907
Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells., PMID:19671067
Effect of allyl alcohol on hepatic transporter expression: zonal patterns of expression and role of Kupffer cell function., PMID:19371622
Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4)., PMID:18612080
Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4., PMID:18559527
Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells., PMID:17318419
Mrp4 confers resistance to topotecan and protects the brain from chemotherapy., PMID:15314169
The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage., PMID:15297306
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane., PMID:12883481
For research use only. Not for human or drug use.
