Catalog No.
PHB61301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ABCB11 (Glu421-Ala663).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
BSEP, Bile salt export pump, ABCB11, ATP-binding cassette sub-family B member 11
Purification
Purified by antigen affinity column.
Accession
O95342
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Interrupting tumor necrosis factor-alpha signaling prevents parenteral nutrition-associated cholestasis in mice., PMID:34664730
Bsep expression in hilar cholangiocarcinoma of rat model., PMID:33536605
Alloimmunity and Cholestasis After Liver Transplantation in Children With Progressive Familial Intrahepatic Cholestasis., PMID:30664572
Allogeneic haematopoietic stem cell transplantation eliminates alloreactive inhibitory antibodies after liver transplantation for bile salt export pump deficiency., PMID:29935200
Post-transplant Recurrent Bile Salt Export Pump Disease: A Form of Antibody-mediated Graft Dysfunction and Utilization of C4d., PMID:28945205
Cholestasis After Pediatric Liver Transplantation-Recurrence of a Progressive Familial Intrahepatic Cholestasis Phenotype as a Rare Differential Diagnosis: A Case Report., PMID:28838453
Persisting hyperbilirubinemia in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with eculizumab: The role of hepatocanalicular transporter variants., PMID:28692147
Recurrence of Progressive Familial Intrahepatic Cholestasis Type 2 Phenotype After Living-donor Liver Transplantation: A Case Report., PMID:27932171
High affinity anti-BSEP antibodies after liver transplantation for PFIC-2 - Successful treatment with immunoadsorption and B-cell depletion., PMID:27368585
Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats., PMID:27090119
Bile salt export pump-reactive antibodies form a polyclonal, multi-inhibitory response in antibody-induced bile salt export pump deficiency., PMID:26516723
Abnormal Localization of STK17A in Bile Canaliculi in Liver Allografts: An Early Sign of Chronic Rejection., PMID:26305096
Autoimmune BSEP disease: disease recurrence after liver transplantation for progressive familial intrahepatic cholestasis., PMID:25342496
Anti-CD20 Monoclonal Antibody Therapy in Functional Bile Salt Export Pump Deficiency After Liver Transplantation., PMID:24231640
Rituximab as therapy for the recurrence of bile salt export pump deficiency after liver transplantation., PMID:24115678
Cholestatic liver disease., PMID:23797137
A novel mutation within a transmembrane helix of the bile salt export pump (BSEP, ABCB11) with delayed development of cirrhosis., PMID:23758865
Anti-tumor necrosis factor-α monoclonal antibody alleviates parenteral nutrition-associated liver disease in mice., PMID:22275328
Relapsing features of bile salt export pump deficiency after liver transplantation in two patients with progressive familial intrahepatic cholestasis type 2., PMID:20800306
Recurrence of bile salt export pump deficiency after liver transplantation., PMID:19797282
De novo bile salt transporter antibodies as a possible cause of recurrent graft failure after liver transplantation: a novel mechanism of cholestasis., PMID:19642168
Expression, localization, and inducibility by bile acids of hepatobiliary transporters in the new polarized rat hepatic cell lines, Can 3-1 and Can 10., PMID:17909858
Sepsis-associated cholestasis is critically dependent on P-selectin-dependent leukocyte recruitment in mice., PMID:17255363
A new ABCB11 mutation in two Italian children with familial intrahepatic cholestasis., PMID:16868810
Benign recurrent intrahepatic cholestasis associated with mutations of the bile salt export pump., PMID:16394881
Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B., PMID:16109175
Differential expression of bile salt and organic anion transporters in developing rat liver., PMID:15288467
LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process., PMID:15205115
Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase., PMID:14762791
Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis., PMID:14568249
Estradiol-17beta-D-glucuronide induces endocytic internalization of Bsep in rats., PMID:12702498
Asynchronous expression and colocalization of Bsep and Mrp2 during development of rat liver., PMID:11842005
Molecular cloning and characterization of the murine bile salt export pump., PMID:10607905
Identification of a sister gene to P-glycoprotein., PMID:7538046
For research use only. Not for human or drug use.
