Catalog No.
PHJ39901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human LRIG1 (Cys45-Val397).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LIG-1, Leucine-rich repeats and immunoglobulin-like domains protein 1, LIG1, LRIG1
Purification
Purified by antigen affinity column.
Accession
Q96JA1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Lrig1-expression confers suppressive function to CD4+ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis., PMID:37666819
A member of the immunoglobulin superfamily lrig-1 might be involved in the immune priming of Scylla paramamosain in response to the infection and re-infection by Vibrio parahaemolyticus., PMID:37302729
miR-301a-3p induced by endoplasmic reticulum stress mediates the occurrence and transmission of trastuzumab resistance in HER2-positive gastric cancer., PMID:34257270
Leucine-rich Repeats and Immunoglobulin 1 (LRIG1) Ameliorates Liver Fibrosis and Hepatic Stellate Cell Activation via Inhibiting Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P) Pathway., PMID:33463106
Novel Somatic Genetic Variants as Predictors of Resistance to EGFR-Targeted Therapies in Metastatic Colorectal Cancer Patients., PMID:32796636
Pigment epithelium-derived factor peptide reverses mouse age-related meibomian gland atrophy., PMID:31129251
LRIG1‑2 and LMO7 immunoreactivity in vulvar squamous cell carcinoma: Association with prognosis in relation to HPV‑DNA and p16INK4a status., PMID:31059071
Glucocorticoid Receptor Modulates EGFR Feedback upon Acquisition of Resistance to Monoclonal Antibodies., PMID:31052457
Lrig1 Expression in Human Sebaceous Gland Tumors., PMID:27504445
Immunofluorescence Tomography of Mouse Ocular Surface Epithelial Stem Cells and Their Niche Microenvironment., PMID:26559480
LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice., PMID:25921371
Construction of human LRIG1-TAT fusions and TAT-mediated LRIG1 protein delivery., PMID:25661388
Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine., PMID:25460603
USP8 modulates ubiquitination of LRIG1 for Met degradation., PMID:24828152
Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody., PMID:23208509
Paneth cells in intestinal homeostasis and tissue injury., PMID:22745693
Stem cell dynamics in sebaceous gland morphogenesis in mouse skin., PMID:22227295
LRIG1 protein in human cells and tissues., PMID:12684867
For research use only. Not for human or drug use.
