Catalog No.
PHF65501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CNTNAP1 (Pro926-Glu1190).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Contactin-associated protein 1, p190, NRXN4, CNTNAP1, CASPR, Caspr1, Neurexin-4, Neurexin IV, Caspr
Purification
Purified by antigen affinity column.
Accession
P78357
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Anti-contactin-associated protein 1 antibody-positive nodopathy presenting with central nervous system symptoms., PMID:39084134
Leucine-Rich Glioma-Inactivated 1 versus Contactin-Associated Protein-like 2 Antibody Neuropathic Pain: Clinical and Biological Comparisons., PMID:34370313
Antibodies to the Caspr1/contactin-1 complex in chronic inflammatory demyelinating polyradiculoneuropathy., PMID:33880507
Peripheral nerve hyperexcitability syndrome: A clinical, electrophysiological, and immunological study., PMID:33501683
Generation of High-Yield, Functional Oligodendrocytes from a c-myc Immortalized Neural Cell Line, Endowed with Staminal Properties., PMID:33498778
Antiparanodal antibodies and IgG subclasses in acute autoimmune neuropathy., PMID:32736337
Antibodies to neurofascin, contactin-1, and contactin-associated protein 1 in CIDP: Clinical relevance of IgG isotype., PMID:31753915
Behaviour and neuropathology in mice injected with human contactin-associated protein 2 antibodies., PMID:31079141
Anti-CNTN1 IgG3 induces acute conduction block and motor deficits in a passive transfer rat model., PMID:30953561
Increased adverse events associated with antiepileptic drugs in anti-leucine-rich glioma-inactivated protein 1 encephalitis., PMID:30159879
Autoantibodies Against the Node of Ranvier in Seropositive Chronic Inflammatory Demyelinating Polyneuropathy: Diagnostic, Pathogenic, and Therapeutic Relevance., PMID:29867996
Brain-relevant antibodies in first-episode psychosis: a matched case-control study., PMID:28920570
IgG4 anti-neurofascin155 antibodies in chronic inflammatory demyelinating polyradiculoneuropathy: Clinical significance and diagnostic utility of a conventional assay., PMID:27852440
Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy., PMID:27474220
Contactin-1 IgG4 antibodies cause paranode dismantling and conduction defects., PMID:27017186
[Morvan's syndrome (Morvan's fibrillary chorea)]., PMID:26480798
Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain., PMID:24685353
Neutralization of inhibitory molecule NG2 improves synaptic transmission, retrograde transport, and locomotor function after spinal cord injury in adult rats., PMID:23447612
Nodes of ranvier and paranodes in chronic acquired neuropathies., PMID:21267074
Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury., PMID:17662136
No effect of genetic deletion of contactin-associated protein (CASPR) on axonal orientation and synaptic plasticity., PMID:17549747
Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve., PMID:16828970
Connexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning., PMID:16203097
Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier., PMID:16039564
Changes in the expression and localization of the paranodal protein Caspr on axons in chronic multiple sclerosis., PMID:12805111
Protein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibres., PMID:12542678
Neurofascin is a glial receptor for the paranodin/Caspr-contactin axonal complex at the axoglial junction., PMID:11839274
Protein zero is necessary for E-cadherin-mediated adherens junction formation in Schwann cells., PMID:11749037
Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination., PMID:11069942
For research use only. Not for human or drug use.
