Catalog No.
PHG26601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD157/BST1 (Arg63-Ala313).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, Bone marrow stromal antigen 1, BST-1, ADP-ribosyl cyclase 2, CD157, Cyclic ADP-ribose hydrolase 2, BST1, cADPr hydrolase 2
Purification
Purified by antigen affinity column.
Accession
Q10588
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
CD157 Can Replace CD24 and CD14 in a Single-Tube Flow-Cytometric Assay to Detect Paroxysmal Nocturnal Hemoglobinuria (PNH) Clones on Both Neutrophils and Monocytes: A Prospective Study From North India., PMID:35415060
A new strategy to count and sort neutrophil-derived extracellular vesicles: Validation in infectious disorders., PMID:35362257
CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1., PMID:34707185
[Contribution and limits of CD157 in the detection of the paroxysmal nocturnal hemoglobinuria clone: a case report]., PMID:34427564
A Prospective, Cross Sectional Study of PNH Clone in MDS Patients Using High Sensitivity Flowcytometry: A Single Center Experience., PMID:32647427
CD157: From Myeloid Cell Differentiation Marker to Therapeutic Target in Acute Myeloid Leukemia., PMID:31817547
Re: Blaha J et al.: The monoclonal anti-CD157 antibody clone SY11B5, used for high sensitivity detection of PNH clones on WBCs, fails to detect a common polymorphic variant encoded by BST-1., PMID:30353646
CD157: From immunoregulatory protein to potential therapeutic target., PMID:29936181
High sensitivity 8-color flow cytometry assay for paroxysmal nocturnal hemoglobinuria granulocyte and monocyte detections., PMID:29599976
Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells., PMID:29549115
The Monoclonal Anti-CD157 Antibody Clone SY11B5, Used for High Sensitivity Detection of PNH Clones on WBCs, Fails to Detect a Common Polymorphic Variant Encoded by BST-1., PMID:29360268
Targeting CD157 in AML using a novel, Fc-engineered antibody construct., PMID:28415689
High-Sensitivity Detection of PNH Red Blood Cells, Red Cell Precursors, and White Blood Cells., PMID:25827482
Loss of lymph node fibroblastic reticular cells and high endothelial cells is associated with humoral immunodeficiency in mouse graft-versus-host disease., PMID:25422510
The CD157-integrin partnership controls transendothelial migration and adhesion of human monocytes., PMID:21478153
Functional role and prognostic significance of CD157 in ovarian carcinoma., PMID:20639476
Antibodies to glycosylphosphatidyl-inositol anchored proteins (GPI-AP) in antithymocyte and antilymphocyte globulin: possible role for the expansion of GPI-AP deficient cells in aplastic anemia., PMID:19137453
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology., PMID:18626062
The CD38/CD157 mammalian gene family: An evolutionary paradigm for other leukocyte surface enzymes., PMID:18404481
CD157 is part of a supramolecular complex with CD11b/CD18 on the human neutrophil cell surface., PMID:18211745
Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer's patches., PMID:17442949
Weak interaction between inhibition peptides and a soluble receptor of fusion protein in the liquid phase., PMID:16966807
CD157 plays a pivotal role in neutrophil transendothelial migration., PMID:16917007
CD157 undergoes ligand-independent dimerization and colocalizes with caveolin in CHO and MCA102 fibroblasts., PMID:12220619
Signalling of GPI-anchored CD157 via focal adhesion kinase in MCA102 fibroblasts., PMID:11602246
An immature rat lymphocyte marker CD157: striking differences in the expression between mice and rats., PMID:11563673
Modulation of CD157 expression in multi-lineage myeloid differentiation of promyelocytic cell lines., PMID:11089918
BST-1/CD157 regulates the humoral immune responses in vivo., PMID:10851788
Novel kinetics, behaviour and cell-type specificity of CD157-mediated tyrosine kinase signalling., PMID:10659997
Expression of homing receptors and related molecules on human mast cells and basophils: a comparative analysis using multi-color flow cytometry and toluidine blue/immunofluorescence staining techniques., PMID:10599889
Deletion of bone marrow stromal cell antigen-1 (CD157) gene impaired systemic thymus independent-2 antigen-induced IgG3 and mucosal TD antigen-elicited IgA responses., PMID:9780166
Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies., PMID:9764855
Nurse-like cells from bone marrow and synovium of patients with rheumatoid arthritis promote survival and enhance function of human B cells., PMID:9691097
For research use only. Not for human or drug use.
