Catalog No.
PHF26201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ANTXR2 (Gln34-Gly318).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CMG-2, ANTXR2, Anthrax toxin receptor 2, Capillary morphogenesis gene 2 protein, CMG2
Purification
Purified by antigen affinity column.
Accession
P58335
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Anthrax toxin receptor 2 is a potential therapeutic target for non-small cell lung carcinoma with MET exon 14 skipping mutations., PMID:35189107
Binding of the von Willebrand Factor A Domain of Capillary Morphogenesis Protein 2 to Anthrax Protective Antigen Vaccine Reduces Immunogenicity in Mice., PMID:31941807
Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration., PMID:29562594
Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamiana., PMID:28054967
Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors., PMID:27864696
Recombinant HSA-CMG2 Is a Promising Anthrax Toxin Inhibitor., PMID:26805881
The Disulfide Bond Cys255-Cys279 in the Immunoglobulin-Like Domain of Anthrax Toxin Receptor 2 Is Required for Membrane Insertion of Anthrax Protective Antigen Pore., PMID:26107617
Improving the anti-toxin abilities of the CMG2-Fc fusion protein with the aid of computational design., PMID:25101992
Targeted silencing of anthrax toxin receptors protects against anthrax toxins., PMID:24742682
Selective blockade of tumor angiogenesis., PMID:22617387
Transient co-expression of post-transcriptional gene silencing suppressors for increased in planta expression of a recombinant anthrax receptor fusion protein., PMID:21954339
Heterodimeric integrin complexes containing beta1-integrin promote internalization and lethality of anthrax toxin., PMID:20713715
Production of recombinant anthrax toxin receptor (ATR/CMG2) fused with human Fc in planta., PMID:19796689
The inhibition of the interaction between the anthrax toxin and its cellular receptor by an anti-receptor monoclonal antibody., PMID:19486894
Efficient neutralization of antibody-resistant forms of anthrax toxin by a soluble receptor decoy inhibitor., PMID:19075066
The CMG2 ELISA for evaluating inhibitors of the binding of anthrax toxin protective antigen to its receptor., PMID:19049885
A viral nanoparticle with dual function as an anthrax antitoxin and vaccine., PMID:17922572
Anthrax toxin receptor 2-dependent lethal toxin killing in vivo., PMID:17054395
Detection of anthrax toxin in the serum of animals infected with Bacillus anthracis by using engineered immunoassays., PMID:16760326
The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin., PMID:16564009
For research use only. Not for human or drug use.
