Catalog No.
PHD54101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TGM1 (Ser467-Ala817).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
KTG, Transglutaminase K, Epidermal TGase, Protein-glutamine gamma-glutamyltransferase K, TGK, TGase K, TGase-1, TGM1, TG(K), Transglutaminase-1
Purification
Purified by antigen affinity column.
Accession
P22735
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Cornification of keratinocytes is associated with differential changes in the catalytic activity and the immunoreactivity of transglutaminase-1., PMID:38057394
Patients with congenital ichthyosis and TGM1 mutations overexpress other ARCI genes in the skin: Part of a barrier repair response?, PMID:30372788
Transglutaminases in autoimmune and inherited skin diseases: The phenomena of epitope spreading and functional compensation., PMID:28940785
A covalent and cleavable antibody-DNA conjugation strategy for sensitive protein detection via immuno-PCR., PMID:26947912
Identification of two novel nonsense mutations in the transglutaminase 1 gene in a Hungarian patient with congenital ichthyosiform erythroderma., PMID:12823447
A novel homozygous mutation 371delA in TGM1 leads to a classic lamellar ichthyosis phenotype., PMID:12534611
Novel mutations of TGM1 in a child with congenital ichthyosiform erythroderma., PMID:11251583
A novel in situ method for the detection of deficient transglutaminase activity in the skin., PMID:9860283
Localization and topography of antigenic domains within the heavy chain of smooth muscle myosin., PMID:2409097
For research use only. Not for human or drug use.
