Catalog No.
PHJ77101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD312/ADGRE2 (Asn347-Ser509).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
EMR2, EGF-like module receptor 2, ADGRE2, EGF-like module-containing mucin-like hormone receptor-like 2, Adhesion G protein-coupled receptor E2, CD312
Purification
Purified by antigen affinity column.
Accession
Q9UHX3
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes., PMID:33488598
Historical Anecdotes and Breakthroughs of Histamine: From Discovery to Date., PMID:32727338
G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:31969668
Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies., PMID:31273197
Composition of lymphocyte subpopulations in normal canine lymph nodes., PMID:25512102
Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas., PMID:25200831
EMR2 receptor ligation modulates cytokine secretion profiles and cell survival of lipopolysaccharide-treated neutrophils., PMID:22035891
F4/80 and the related adhesion-GPCRs., PMID:21952799
Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function., PMID:17928360
Detection of novel leukocyte differentiation antigens on basophils and mast cells by HLDA8 antibodies., PMID:16918507
Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue., PMID:15693006
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells., PMID:15498814
The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans., PMID:12829604
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells., PMID:11994511
Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97., PMID:10903844
For research use only. Not for human or drug use.
