Catalog No.
PHD03501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human FOLR2 (Thr17-Asn230).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
FBP, FOLR2, Folate receptor beta, Placental folate-binding protein, Folate receptor, fetal/placental, FR-beta, Folate receptor 2
Purification
Purified by antigen affinity column.
Accession
P14207
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Mirvetuximab soravtansine-gynx: first antibody/antigen-drug conjugate (ADC) in advanced or recurrent ovarian cancer., PMID:38101816
Recent Advances in Folates and Autoantibodies against Folate Receptors in Early Pregnancy and Miscarriage., PMID:38068740
FDA Approval Summary: Mirvetuximab Soravtansine-Gynx for FRα-Positive, Platinum-Resistant Ovarian Cancer., PMID:37212825
Folate Receptor Beta as a Direct and Indirect Target for Antibody-Based Cancer Immunotherapy., PMID:34070369
Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats., PMID:31796042
Genetic assessment and folate receptor autoantibodies in infantile-onset cerebral folate deficiency (CFD) syndrome., PMID:29661558
High-affinity FRβ-specific CAR T cells eradicate AML and normal myeloid lineage without HSC toxicity., PMID:26898190
Atypical Activin A and IL-10 Production Impairs Human CD16+ Monocyte Differentiation into Anti-Inflammatory Macrophages., PMID:26729812
Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile., PMID:25319955
Importance of folate-homocysteine homeostasis during early embryonic development., PMID:18067451