Catalog No.
PHC31101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SERPINA6 (Leu280-Val405).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Corticosteroid-binding globulin, Serpin A6, Transcortin, CBG, SERPINA6
Purification
Purified by antigen affinity column.
Accession
P08185
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Pyrexia and acidosis act independently of neutrophil elastase reactive center loop cleavage to effect cortisol release from corticosteroid-binding globulin., PMID:33085168
The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates., PMID:29307512
Monoclonal antibodies to the reactive centre loop (RCL) of human corticosteroid-binding globulin (CBG) can protect against proteolytic cleavage., PMID:28411181
Identification of Avian Corticosteroid-binding Globulin (SerpinA6) Reveals the Molecular Basis of Evolutionary Adaptations in SerpinA6 Structure and Function as a Steroid-binding Protein., PMID:27026706
Corticosteroid-binding globulin (CBG) reactive centre loop antibodies and surface plasmon resonance interrogate the proposed heat dependent "flip-flop" mechanism of human CBG., PMID:26829559
Expression of corticosterone-binding globulin in the rat hypothalamus., PMID:16700006
Detection of a CBG-like protein in human Fallopian tube tissue., PMID:14871264
Disappearance of M(r) 25,000 protein, a new protein kinase substrate, in parallel with a kind of serpin during embryogenesis., PMID:12186765
Interactions of serine proteinases with pNiXa, a serpin of Xenopus oocytes and embryos., PMID:9540798
Characterization of pNiXa, a serpin of Xenopus laevis oocytes and embryos, and its histidine-rich, Ni(II)-binding domain., PMID:8844694
Immunoperoxidase staining of tumors by an antibody to Xenopus pNiXa., PMID:8726217
Rat corticosteroid-binding globulin (CBG) biosynthesis by fetal hepatocytes in culture., PMID:3897715
For research use only. Not for human or drug use.
