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Anti-LOXL1 Polyclonal Antibody

Catalog #:   PHG16301 Specific References (24) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q08397
Overview

Catalog No.

PHG16301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LOXL1 (Leu369-Ser574).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Lysyl oxidase homolog 1, LOXL1, LOXL, Lysyl oxidase-like protein 1, LOL

Purification

Purified by antigen affinity column.

Accession

Q08397

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with LOXL1 antibody (PHG16301) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 26 kDa
    Observed MW: 26 kDa
References

The molecular features of chronic lung allograft dysfunction in lung transplant airway mucosa., PMID:36163162

Compositional Analysis of Extracellular Aggregates in the Eyes of Patients With Exfoliation Syndrome and Exfoliation Glaucoma., PMID:34964803

Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis., PMID:32176358

Posttranscriptional Regulation of LOXL1 Expression Via Alternative Splicing and Nonsense-Mediated mRNA Decay as an Adaptive Stress Response., PMID:29164236

Oxidized low density lipoprotein facilitates tumor necrosis factor‑α mediated chondrocyte death via autophagy pathway., PMID:29039543

Platelet-rich plasma induces post-natal maturation of immature articular cartilage and correlates with LOXL1 activation., PMID:28623328

Hypoxia triggers angiogenesis by increasing expression of LOX genes in 3-D culture of ASCs and ECs., PMID:28189640

Targeting lysyl oxidase for molecular imaging in breast cancer., PMID:26265048

Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction., PMID:26260798

Elastin development-associated extracellular matrix constituents of subepithelial connective tissue in human pterygium., PMID:25183766

Disruption of the blood-aqueous barrier and lens abnormalities in mice lacking lysyl oxidase-like 1 (LOXL1)., PMID:24425853

Changes in lysyl oxidase (LOX) distribution and its decreased activity in keratoconus corneas., PMID:23041260

LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma., PMID:22633114

Atomic force microscopy-based antibody recognition imaging of proteins in the pathological deposits in pseudoexfoliation syndrome., PMID:21740868

Differential expression of elastic fibre components in intrinsically aged skin., PMID:21461665

Lysyl oxidase activity is dysregulated during impaired alveolarization of mouse and human lungs., PMID:19797161

Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes., PMID:19394199

Analysis of dermal elastic fibers in the absence of fibulin-5 reveals potential roles for fibulin-5 in elastic fiber assembly., PMID:19321153

Lysyl oxidase like-1 dysregulation and its contribution to direct inguinal hernia., PMID:19292889

Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1., PMID:18296663

Down-regulation of lysyl oxydase-like in aging and venous insufficiency., PMID:17999374

The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers., PMID:16251195

Elastic fiber homeostasis requires lysyl oxidase-like 1 protein., PMID:14745449

Lysyl oxidase-like protein from bovine aorta. Isolation and maturation to an active form by bone morphogenetic protein-1., PMID:11684696

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-LOXL1 Polyclonal Antibody [PHG16301]
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