Catalog No.
PHJ18901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SULF2 (Phe337-Arg649).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Extracellular sulfatase Sulf-2, KIAA1247, SULF2, hSulf-2
Purification
Purified by antigen affinity column.
Accession
Q8IWU5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2., PMID:38825040
Galectin-3-binding protein inhibits extracellular heparan 6-O-endosulfatse Sulf-2., PMID:38187586
Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches., PMID:34324645
Sulfatase 2 (SULF2) Monoclonal Antibody 5D5 Suppresses Human Cholangiocarcinoma Xenograft Growth Through Regulation of a SULF2-Platelet-Derived Growth Factor Receptor Beta-Yes-Associated Protein Signaling Axis., PMID:33735525
Expression of the Extracellular Sulfatase SULF2 Affects Survival of Head and Neck Squamous Cell Carcinoma Patients., PMID:33585200
Detection of selection signatures for response to Aleutian mink disease virus infection in American mink., PMID:33536540
Association between herpes simplex virus 1 exposure and the risk of depression in UK Biobank., PMID:32564518
Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling., PMID:27294358
SULF1/SULF2 reactivation during liver damage and tumour growth., PMID:27013228
SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer., PMID:26882224
Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma., PMID:25449037
Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro., PMID:25448158
SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis., PMID:25444749
Role of 6-O-sulfated heparan sulfate in chronic renal fibrosis., PMID:24878958
SULF2 expression by immunohistochemistry and overall survival in oesophageal cancer: a cohort study., PMID:23180455
Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation., PMID:23136428
Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients., PMID:22429964
The role of glypican-3 in regulating Wnt in hepatocellular carcinomas., PMID:22563565
Use of a phage display antibody to measure the enzymatic activity of the Sulfs., PMID:20816204
Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88., PMID:19822709
Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity., PMID:16901266