Catalog No.
PHJ46401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TIMP4 (Cys32-Pro224).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TIMP-4, Tissue inhibitor of metalloproteinases 4, TIMP4, Metalloproteinase inhibitor 4
Purification
Purified by antigen affinity column.
Accession
Q99727
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Plasma levels of multiple cardiovascular- and inflammation-related proteins analysed for associations with disease activity and anti-cyclic citrullinated peptide status in active early rheumatoid arthritis., PMID:36995323
Aloperine Prevents Migration, Invasion, and Adhesion by Upregulating TIMP-4 in Human Bladder Cancer Cells., PMID:36734907
A descriptive analysis of non-human leukocyte antigens present in renal transplant donor-recipient pairs., PMID:34582968
Transient association between semen exposure and biomarkers of genital inflammation in South African women at risk of HIV infection., PMID:34164927
Non-invasive Embryo Assessment: Altered Individual Protein Profile in Spent Culture Media from Embryos Transferred at Day 5., PMID:33151525
Monoclonal Antibody against CXCL1 (HL2401) as a Novel Agent in Suppressing IL6 Expression and Tumoral Growth., PMID:30809313
Protein array profiling of circulating angiogenesis-related factors during bevacizumab containing treatment in metastatic colorectal cancer., PMID:30592740
Sex steroids drive the remodeling of oviductal extracellular matrix in cattle., PMID:29659700
Effects of C-reactive protein on the expression of matrix metalloproteinases and their inhibitors via Fcγ receptors on 3T3-L1 adipocytes., PMID:28539825
Modulation of Matrix Metalloproteinase 14, Tissue Inhibitor of Metalloproteinase 3, Tissue Inhibitor of Metalloproteinase 4, and Inducible Nitric Oxide Synthase in the Development of Periapical Lesions., PMID:28527839
Microbial Translocation Associated with an Acute-Phase Response and Elevations in MMP-1, HO-1, and Proinflammatory Cytokines in Strongyloides stercoralis Infection., PMID:27821584
Expression and characterization of tissue inhibitor of metalloproteinase 4 from complex canine mammary carcinomas., PMID:26979595
Dynamic regulation of plasma matrix metalloproteinases in human diabetic ketoacidosis., PMID:26492282
Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion., PMID:25978399
Cardiac tissue inhibitor of matrix metalloprotease 4 dictates cardiomyocyte contractility and differentiation of embryonic stem cells into cardiomyocytes: Road to therapy., PMID:25745981
Elevated plasma angiogenesis factors in Alzheimer's disease., PMID:25690662
Simultaneous study of matrix metalloproteinases, proinflammatory cytokines, and soluble cytokine receptors in the tears of noninfectious corneal ulcer patients., PMID:25005620
Identification of five serum protein markers for detection of ovarian cancer by antibody arrays., PMID:24116163
Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units., PMID:23851162
Hypoxia inhibits cardiomyocyte proliferation in fetal rat hearts via upregulating TIMP-4., PMID:23427085
Interleukin-17F affects cartilage matrix turnover by increasing the expression of collagenases and stromelysin-1 and by decreasing the expression of their inhibitors and extracellular matrix components in chondrocytes., PMID:21885294
Matrix metalloproteinase-1 expression enhances tumorigenicity as well as tumor-related angiogenesis and is inversely associated with TIMP-4 expression in a model of glioblastoma., PMID:21858729
Elevated plasma matrix metalloproteinases and their tissue inhibitors in patients with severe sepsis., PMID:21439766
[The mechanism of lung tissue remodeling in the progression of idiopathic pulmonary fibrosis]., PMID:21086635
Development of a monoclonal antibody that specifically detects tissue inhibitor of metalloproteinase-4 (TIMP-4) in formalin-fixed, paraffin-embedded human tissues., PMID:20564221
Type-specific dysregulation of matrix metalloproteinases and their tissue inhibitors in end-stage heart failure patients: relationship between MMP-10 and LV remodelling., PMID:20219015
Prostasin inhibits cell invasion in human choriocarcinomal JEG-3 cells., PMID:19847458
A study of matrix metalloproteinase expression and activity in atopic dermatitis using a novel skin wash sampling assay for functional biomarker analysis., PMID:19804592
Effects of AT1- and beta-adrenergic receptor antagonists on TGF-beta1-induced fibrosis in transgenic mice., PMID:19522835
Vascular regression and survival are differentially regulated by MT1-MMP and TIMPs in the aortic ring model of angiogenesis., PMID:19494241
Analysis of alpha2-adrenergic receptors and effect of brimonidine on matrix metalloproteinases and their inhibitors in human ciliary body., PMID:19324857
Catabolic properties of microdissected human endosteal bone lining cells., PMID:19139801
[Clinical and morphological parallels and molecular aspects of the morphogenesis of adenomyosis]., PMID:19137775
Atrial extracellular matrix remodelling in patients with atrial fibrillation., PMID:18194448
Association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis., PMID:18187780
Expression of matrix metalloproteinase-26 and tissue inhibitors of metalloproteinase-3 and -4 in normal ovary and ovarian carcinoma., PMID:17009974
Desiccating stress stimulates expression of matrix metalloproteinases by the corneal epithelium., PMID:16877394
Proteinase and growth factor alterations revealed by gene microarray analysis of human diabetic corneas., PMID:16186340
The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling., PMID:14734772
Expression of matrix metalloproteinase-26 and tissue inhibitors of metalloproteinases TIMP-3 and -4 in benign endometrium and endometrial cancer., PMID:12798711
Expression and implications of tissue inhibitor of metalloproteinases-4 in mouse embryo., PMID:12606590
Complexes of gelatinases and tissue inhibitor of metalloproteinases in human seminal plasma., PMID:12514086
Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs)., PMID:12154073
Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes., PMID:12008026
Mutation in collagen gene induces cardiomyopathy in transgenic mice., PMID:11948682
Induction of oxidative stress by homocyst(e)ine impairs endothelial function., PMID:11500925
Development and characterization of a new polyclonal antibody specifically against tissue inhibitor of metalloproteinases 4 in human breast cancer., PMID:11178975
Preparation and characterization of recombinant tissue inhibitor of metalloproteinase 4 (TIMP-4)., PMID:9252358
For research use only. Not for human or drug use.
