Catalog No.
PHE38801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SLC1A1 (Ser115-Gly209).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
EAAC1, EAAT3, Sodium-dependent glutamate/aspartate transporter 3, Solute carrier family 1 member 1, Excitatory amino-acid carrier 1, SLC1A1, Excitatory amino acid transporter 3, Neuronal and epithelial glutamate transporter
Purification
Purified by antigen affinity column.
Accession
P43005
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Oral exposure to nanoplastics and food allergy in mice fed a normal or high-fat diet., PMID:40252413
A spatiotemporal map of co-receptor signaling networks underlying B cell activation., PMID:38850533
SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential., PMID:34628354
Expression of Glutamate Transporters in Mouse Liver, Kidney, and Intestine., PMID:29303644
Reduced responses to glutamate receptor agonists follow loss of astrocytes and astroglial glutamate markers in the nucleus tractus solitarii., PMID:28270593
Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression., PMID:27807832
Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1., PMID:26739563
Chronic exposure to morphine decreases the expression of EAAT3 via opioid receptors in hippocampal neurons., PMID:25839761
The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS., PMID:22539860
Specificity controls for immunocytochemistry: the antigen preadsorption test can lead to inaccurate assessment of antibody specificity., PMID:22215633
Changes in glutamate transporter expression in mouse forebrain areas following focal ischemia., PMID:21911209
Regulation of glutamate transporter GLT-1 by MAGI-1., PMID:21426345
Platelet-derived growth factor receptor alpha is associated with oxidative stress-induced retinal cell death., PMID:21405954
Group I mGluR-regulated translation of the neuronal glutamate transporter, excitatory amino acid carrier 1., PMID:21371038
Inhibition of isoflurane-induced increase of cell-surface redistribution and activity of glutamate transporter type 3 by serine 465 sequence-specific peptides., PMID:21266171
Expression and distribution of 'high affinity' glutamate transporters GLT1, GLAST, EAAC1 and of GCPII in the rat peripheral nervous system., PMID:19014361
Cytogenesis in the dentate gyrus after neonatal hyperthermia-induced seizures: what becomes of surviving cells?, PMID:18076639
Glutamate receptor expression in multiple sclerosis lesions., PMID:17924980
TNFR1 mediates increased neuronal membrane EAAT3 expression after in vivo cerebral ischemic preconditioning., PMID:16442237
Expression of glutamate transporter subtypes during normal human corticogenesis and type II lissencephaly., PMID:15804404
Isoflurane induces a protein kinase C alpha-dependent increase in cell-surface protein level and activity of glutamate transporter type 3., PMID:15709112
Mercury compounds disrupt neuronal glutamate transport in cultured mouse cerebellar granule cells., PMID:15635608
Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini., PMID:15569258
Expression of glutamate transporters in rat cardiomyocytes and their localization in the T-tubular system., PMID:15385585
Retinal colocalization and in vitro interaction of the glutamate transporter EAAT3 and the serum- and glucocorticoid-inducible kinase SGK1 [correction]., PMID:15111600
In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway., PMID:14960606
Identification of glutamate receptors and transporters in mouse and human sperm., PMID:14662797
Neuronal glutamate transporter EAAT4 is expressed in astrocytes., PMID:12951653
Expression of glutamate transporters in human and rat retina and rat optic nerve., PMID:12898275
Decreased expression of glutamate transporters in genetic absence epilepsy rats before seizure occurrence., PMID:11953453
Increased expression of the neuronal glutamate transporter (EAAT3/EAAC1) in hippocampal and neocortical epilepsy., PMID:11906504
Nigrostriatal denervation does not affect glutamate transporter mRNA expression but subsequent levodopa treatment selectively increases GLT1 mRNA and protein expression in the rat striatum., PMID:11723182
Glutamate transporter EAAC1 is expressed on Müller cells of lower vertebrate retinas., PMID:11599005
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1., PMID:11426296
Antisense knockdown of glutamate transporters alters the subfield selectivity of kainate-induced cell death in rat hippocampal slice cultures., PMID:10537040
Glutamate transporter EAAC1 is expressed in neurons and glial cells in the rat nervous system., PMID:10417812
Changes in expression of neuronal and glial glutamate transporters in rat hippocampus following kainate-induced seizure activity., PMID:10036313
Comparative analysis of glutamate transporter expression in rat brain using differential double in situ hybridization., PMID:9683064
Neuronal expression of the glutamate transporter GLT-1 in hippocampal microcultures., PMID:9614226
The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: a glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia., PMID:9570792
EAAC1, a high-affinity glutamate tranporter, is localized to astrocytes and gabaergic neurons besides pyramidal cells in the rat cerebral cortex., PMID:9542890
Rat hepatoma cells express novel transport systems for glutamine and glutamate in addition to those present in normal rat hepatocytes., PMID:9461518
Localization of the high-affinity glutamate transporter EAAC1 in rat kidney., PMID:9435692
Immunohistochemical localization of the neuron-specific glutamate transporter EAAC1 (EAAT3) in rat brain and spinal cord revealed by a novel monoclonal antibody., PMID:9409715
Glutamate transporter protein subtypes are expressed differentially during rat CNS development., PMID:9334410
Cellular and synaptic localization of the neuronal glutamate transporters excitatory amino acid transporter 3 and 4., PMID:9330365
Expression of high-affinity neuronal and glial glutamate transporters in the rat optic nerve., PMID:9215727