Catalog No.
PHE38501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MTHFR (Met1-Arg325).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Methylenetetrahydrofolate reductase, MTHFR
Purification
Purified by antigen affinity column.
Accession
P42898
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Study of the MTHFR 677C>T Polymorphism in Children and Adolescents with Hashimoto's Thyroiditis: An Original Case-Control Study., PMID:40506882
Timing of diagnostic workups in Chinese population with recurrent pregnancy loss: a cross-sectional study., PMID:40158174
Avascular Necrosis of the Femoral Head in Patients with Antiphospholipid Syndrome: A Case Series., PMID:40126224
Recurrent Early Pregnancy Loss and Congenital Thrombophilia: A Prospective Study., PMID:39598015
MTHFR polymorphisms and vitamin B12 deficiency: correlation between mthfr polymorphisms and clinical and laboratory findings., PMID:39196375
Multi-Gene Single Nucleotide Polymorphism Detection in Gastric Cancer Based on Ion Semiconductor Sequencing Platform., PMID:38801272
Combination of 15q24 Microdeletion Syndrome and Metabolic Imbalance in a Patient with Atypical Autism., PMID:38180598
Interplay between carotid artery dissection and thrombophilia leading to ischaemic stroke after minor head trauma in an adolescent: a case report., PMID:37849317
Evaluation of acquired and hereditary risk factors for the development of thromboembolism in patients with systemic lupus erythematosus., PMID:37756208
Prothrombotic states in portal vein thrombosis and Budd-Chiari syndrome in India: A systematic review and meta-analysis., PMID:37610562
Endothelial dysfunction, thrombophilia, and nailfold capillaroscopic features in livedoid vasculopathy., PMID:37543163
The prognostic role of gene polymorphisms in patients with indolent non-Hodgkin lymphomas and mantle-cell lymphoma receiving bendamustine and rituximab: results of the 5-year follow-up study., PMID:37424258
MTHFR act as a potential cancer biomarker in immune checkpoints blockades, heterogeneity, tumor microenvironment and immune infiltration., PMID:37354330
Chronic Suppurative Otitis Media Patient Presenting With Hyperhomocysteinemia in Granulomatosis With Polyangiitis., PMID:37273400
Dermatological Manifestations in COVID-19: A Case Study of SARS-CoV-2 Infection in a Genetic Thrombophilic Patient with Mthfr Mutation., PMID:36986360
Diagnostic factors for recurrent pregnancy loss: an expanded workup., PMID:36964323
The Proper Diagnosis of Thrombophilic Status in Preventing Fetal Growth Restriction., PMID:36766616
Methylenetetrahydrofolate Reductase 677T Allele Is a Risk Factor for Arterial Thrombosis in Chinese Han Patients with Antiphospholipid Syndrome., PMID:36672563
Folic acid restricts SARS-CoV-2 invasion by methylating ACE2., PMID:36060767
Migraine With Comorbid Depression: Pathogenesis, Clinical Implications, and Treatment., PMID:35865445
Absorption and Tissue Distribution of Folate Forms in Rats: Indications for Specific Folate Form Supplementation during Pregnancy., PMID:35745126
Osteoprotegerin and MTHFR gene variations in rheumatoid arthritis: association with disease susceptibility and markers of subclinical atherosclerosis., PMID:35680906
Association of ALDH2 rs671 and MTHFR rs1801133 polymorphisms with hypertension among Hakka people in Southern China., PMID:35346052
Evaluation of umbilical cord immune cells in pregnancies with autoimmune disorders and/or methylenetetrahydrofolate reductase polymorphisms., PMID:35344642
[The 492nd case: recurrent thrombosis, thrombocytopenia]., PMID:35090264
Singleton pregnancy losses before gestational week 22 among patients with autoimmune disorders and methylenetetrahydrofolate reductase polymorphisms., PMID:35001885
Folic Acid and Autism: A Systematic Review of the Current State of Knowledge., PMID:34440744
Association of increased C-Reactive Protein and hypocomplementemia with risk factors for thrombosis in women who have susceptibility for poor gestational outcome; importance of preconceptional counseling., PMID:34275896
A study of hyperhomocysteinemia in cerebral venous sinus thrombosis., PMID:34145098
Genetic Factors of Predisposition and Clinical Characteristics of Rheumatoid Arthritis in Russian Patients., PMID:34070522
Janus Kinase-2 Mutation Associated Portal Vein Thrombosis Complicating Liver Cirrhosis and Hepatocellular Carcinoma., PMID:33507708
A Association of MTHFR C677T and MTRR A66G Gene Polymorphisms with Iranian Male Infertility and Its Effect on Seminal Folate and Vitamin B12., PMID:33497043
Inherited and acquired thrombophilia in adults with retinal vascular occlusion: A systematic review and meta-analysis., PMID:32805772
Plasma Serotonin is Elevated in Adult Patients with Sudden Sensorineural Hearing Loss., PMID:32717753
DVT and Pulmonary Embolism Following Knee Arthroscopy: The Role of Genetic Predisposition and Autoimmune Antibodies: A Report of 3 Cases., PMID:32649112
Tetra-primer ARMS-PCR combined with GoldMag lateral flow assay for genotyping: simultaneous visual detection of both alleles., PMID:32350488
Immunohistochemical and genetic prognostic factors of neoadjuvant chemoradiotherapy efficаcy in personalized treatment of local advanced rectal cancer., PMID:32285840
The utility of thrombophilia testing in patients with newly diagnosed portal vein thrombosis., PMID:32101880
Thrombophilic risk factors for retinal vein occlusion., PMID:31831825
Acute ischemic stroke in a 7-month-old infant, risk factors, and diagnosis peculiarities: A case report., PMID:31725629
Thrombophilic risk factors in hemodialysis: Association with early vascular access occlusion and patient survival in long-term follow-up., PMID:31539375
Genetic contributors and soluble mediators in prediction of autoimmune comorbidity., PMID:31444033
Spontaneous pregnancies in patients with at least one failed IVF cycle after the management of autoimmune disorders, hereditary thrombophilia, and methylation disorders., PMID:31173496
Retinal vein occlusion in child with rare mutations in genes for thrombophilia., PMID:31173043
Pregnancy outcomes of the patients with anti-smooth muscle antibody positivity., PMID:30909204
Management and the pregnancy outcomes of patients positive for anti-parietal cell antibody., PMID:30594922
Study of gene polymorphisms as predictors of treatment efficacy and toxicity in patients with indolent non-hodgkin lymphomas and mantle cell lymphoma receiving bendamustine and rituximab., PMID:30203425
Comparison of two groups for the apolipoprotein E polymorphisms by using next generation sequencing: The first group with three consecutive abortions and the second group with at most one abortion in three consecutive pregnancies., PMID:29778421
Gene variants in the folate pathway are associated with increased levels of folate receptor autoantibodies., PMID:29732742
Association of MTHFR C677T and A1298C gene polymorphisms with methotrexate efficiency and toxicity in Algerian rheumatoid arthritis patients., PMID:29264421
For research use only. Not for human or drug use.
