Anti-LMAN1 Polyclonal Antibody

Catalog No.

PHE63701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LMAN1 (Pro198-Cys475).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

LMAN1, Protein ERGIC-53, Lectin mannose-binding 1, ERGIC53, Intracellular mannose-specific lectin MR60, ER-Golgi intermediate compartment 53 kDa protein, Gp58, F5F8D

Purification

Purified by antigen affinity column.

Accession

P49257

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Roles of N-glycans in the polymerization-dependent aggregation of mutant Ig-μ chains in the early secretory pathway., PMID:28157181

Subcellular localization of ERGIC-53 under endoplasmic reticulum stress condition., PMID:22821029

Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII., PMID:20817851

A novel missense mutation causing abnormal LMAN1 in a Japanese patient with combined deficiency of factor V and factor VIII., PMID:19787799

Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis., PMID:17805346

ER storage diseases: a role for ERGIC-53 in controlling the formation and shape of Russell bodies., PMID:16735443

Capturing protein interactions in the secretory pathway of living cells., PMID:15849265

Heat shock induces preferential translation of ERGIC-53 and affects its recycling pathway., PMID:15292203

Phtf1 is an integral membrane protein localized in an endoplasmic reticulum domain in maturing male germ cells., PMID:12604659

A functional role for VAP-33 in insulin-stimulated GLUT4 traffic., PMID:11208137

The p58-positive pre-golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H(+)-ATPase., PMID:11017878

Intradermal DNA immunization: antisera specific for the membrane lectin MR60/ERGIC-53., PMID:10841272

Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum., PMID:10559986

Roles for alpha(2)p24 and COPI in endoplasmic reticulum cargo exit site formation., PMID:10427085

Dynamic recycling of ERGIC53 between the endoplasmic reticulum and the Golgi complex is disrupted by nordihydroguaiaretic acid., PMID:9918822

Intracellular localization and in vivo trafficking of p24A and p23., PMID:9914165

Scattered Golgi elements during microtubule disruption are initially enriched in trans-Golgi proteins., PMID:9437000

Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates., PMID:9445473

The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus., PMID:9382863

Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment., PMID:9335259

Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution., PMID:9334349

p53/58 binds COPI and is required for selective transport through the early secretory pathway., PMID:9151666

Identification of two types of beta-COP vesicles in the Golgi complex of rat spermatids., PMID:8905290

Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps., PMID:8522601

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