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Anti-NEO1 Polyclonal Antibody

Catalog #:   PHJ34001 Specific References (15) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q92859
Overview

Catalog No.

PHJ34001

Species reactivity

Human, Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NEO1 (Pro52-Ile426).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

IGDCC2, NEO1, Neogenin, NGN, Immunoglobulin superfamily DCC subclass member 2

Purification

Purified by antigen affinity column.

Accession

Q92859

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with NEO1 antibody (PHJ34001) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 43 kDa
    Observed MW: 43 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with NEO1 antibody (PHJ34001) at 1 μg/ml.

    Lane 1: A549

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 160 kDa
    Observed MW: 160 kDa
  • Immunohistochemical
    Immunohistochemical analysis of human prostate stained for NEO1 with PHJ34001.
References

Targeting RGMb interactions: Discovery and preclinical characterization of potent anti-RGMb antibodies blocking multiple ligand bindings., PMID:39588913

Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling., PMID:37824022

Long-term Safety and Efficacy of Avalglucosidase Alfa in Patients With Late-Onset Pompe Disease., PMID:35618441

A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies., PMID:35348614

Upregulation of Neogenin-1 by a CREB1-BAF47 Complex in Vascular Endothelial Cells is Implicated in Atherogenesis., PMID:35186922

Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer., PMID:32854720

Bispecific antibody (HER2 × mPEG) enhances anti-cancer effects by precise targeting and accumulation of mPEGylated liposomes., PMID:32417267

Hamster neogenin, a host-cell protein contained in a respiratory syncytial virus candidate vaccine, induces antibody responses in rabbits but not in clinical trial participants., PMID:31951765

Safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of the novel enzyme replacement therapy avalglucosidase alfa (neoGAA) in treatment-naïve and alglucosidase alfa-treated patients with late-onset Pompe disease: A phase 1, open-label, multicenter, multinational, ascending dose study., PMID:30770310

Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells., PMID:27288875

Inhibition of neogenin dampens hepatic ischemia-reperfusion injury., PMID:25029243

In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion., PMID:23443137

Immunohistochemical expression of cell differentiation and growth in neonate cardiomyocytes., PMID:22886229

The guidance receptor neogenin promotes pulmonary inflammation during lung injury., PMID:22198383

Embryonic corneal Schwann cells express some Schwann cell marker mRNAs, but no mature Schwann cell marker proteins., PMID:19387082

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-NEO1 Polyclonal Antibody [PHJ34001]
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