Catalog No.
YHB72501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp20-Glu189
Predicted molecular weight
21.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95716
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-3D, RAB3D, GOV, RAB16
Glycosylation Triggers Cathepsin D Maturation and Secretion to Promote Gastric Cancer Development., PMID:40122458
The emerging role of Rab proteins in osteoclast organelle biogenesis and function., PMID:39641593
Delineating molecular regulatory network of meat quality of longissimus dorsi indicated by transcriptomic, proteomic, and metabolomics analysis in rabbit., PMID:38657733
Alcohol-induced Golgiphagy is triggered by the downregulation of Golgi GTPase RAB3D., PMID:38591519
Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B., PMID:38173934
CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588., PMID:37559140
Obstruction of the Tear Drainage Altered Lacrimal Gland Structure and Function., PMID:37440262
[miR-125b-5p inhibits proliferation and migration of osteosarcoma cells by negatively regulating RAB3D expression]., PMID:36856212
Curcumin suppresses lung cancer progression via circRUNX1 mediated miR-760/RAB3D axis., PMID:36523170
The Olfactomedin-4-Defined Human Neutrophil Subsets Differ in Proteomic Profile in Healthy Individuals and Patients with Septic Shock., PMID:36450268
Lymphatic metastasis-associated circRNA‒miRNA‒mRNA network for exploring the pathogenesis and therapeutic target of triple negative breast cancer based on whole-transcriptome sequencing analysis: an experimental verification study., PMID:36335337
RAB3D/MDM2/β-catenin/c-MYC axis exacerbates the malignant behaviors of acute myeloid leukemia cells in vitro and in vivo., PMID:36280757
RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway., PMID:36153645
[The GTP-Bound form of Rab3D Promotes Lipid Droplet Growth in Adipocyte]., PMID:35964313
Porcine circovirus-like virus P1 activates pancreatic secretion pathway by interacting with CHRM3 protein., PMID:35810687
The Construction and Analysis of Immune Infiltration and Competing Endogenous RNA Network in Acute Ischemic Stroke., PMID:35656537
Hsa_circ_0006732 regulates colorectal cancer cell proliferation, invasion and EMT by miR-127-5p/RAB3D axis., PMID:35616807
Hsa_circ_0103232 promotes melanoma cells proliferation and invasion via targeting miR-661/RAB3D., PMID:35549813
CircRNA PRH1-PRR4 stimulates RAB3D to regulate the malignant progression of NSCLC by sponging miR-877-5p., PMID:35076987
Morphological and histochemical characterization of the secretory epithelium in the canine lacrimal gland., PMID:34726360
GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies., PMID:34551092
Alcohol-Induced Liver Injury: Down-regulation and Redistribution of Rab3D Results in Atypical Protein Trafficking., PMID:34494400
Phenylephrine increases tear cathepsin S secretion in healthy murine lacrimal gland acinar cells through an alternative secretory pathway., PMID:34487726
MicroRNA-125a-5p modulates the proliferation and apoptosis of TM4 Sertoli cells by targeting RAB3D and regulating the PI3K/AKT signaling pathway., PMID:34273154
Rab3 proteins and cancer: Exit strategies., PMID:33982832
Long non-coding RNA FGD5-AS1 enhances osteosarcoma cell proliferation and migration by targeting miR-506-3p/RAB3D axis., PMID:33891267
Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells., PMID:33562815
Ras Homolog Family Member F, Filopodia Associated Promotes Hepatocellular Carcinoma Metastasis by Altering the Metabolic Status of Cancer Cells Through RAB3D., PMID:33205519
Oncogenic allelic interaction in Xiphophorus highlights hybrid incompatibility., PMID:33168740
Long Noncoding RNA LINC01133 Promotes the Malignant Behaviors of Renal Cell Carcinoma by Regulating the miR-30b-5p/Rab3D Axis., PMID:33054325
CircRNA hsa_circ_0087862 Acts as an Oncogene in Non-Small Cell Lung Cancer by Targeting miR-1253/RAB3D Axis., PMID:32308420
Lcn2-derived Circular RNA (hsa_circ_0088732) Inhibits Cell Apoptosis and Promotes EMT in Glioma via the miR-661/RAB3D Axis., PMID:32154171
NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis., PMID:30201519
Longitudinal analysis of tear cathepsin S activity levels in male non-obese diabetic mice suggests its potential as an early stage biomarker of Sjögren's Syndrome., PMID:30126300
Identification of lncRNAs and Their Functional Network Associated with Chemoresistance in SW1990/GZ Pancreatic Cancer Cells by RNA Sequencing., PMID:30113217
MicroRNA-506-3p inhibits osteosarcoma cell proliferation and metastasis by suppressing RAB3D expression., PMID:29905536
Molecular architecture of mouse and human pancreatic zymogen granules: protein components and their copy numbers., PMID:29756009
Evaluation of Decellularized Porcine Jejunum as a Matrix for Lacrimal Gland Reconstruction In Vitro for Treatment of Dry Eye Syndrome., PMID:29079859
Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands., PMID:29046053
APE1/Ref-1 knockdown in pancreatic ductal adenocarcinoma - characterizing gene expression changes and identifying novel pathways using single-cell RNA sequencing., PMID:28922540
Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties., PMID:28914590
Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren's Syndrome., PMID:28902875
Silencing of Rab3D suppresses the proliferation and invasion of esophageal squamous cell carcinoma cells., PMID:28472755
Cryopreservation and hypothermic storage of lacrimal gland: towards enabling delivery of regenerative medicine therapies for treatment of dry eye syndrome., PMID:27976538
Calmodulin interacts with Rab3D and modulates osteoclastic bone resorption., PMID:27897225
Molecular Basis for the Protein Recognition Specificity of the Dynein Light Chain DYNLT1/Tctex1: CHARACTERIZATION OF THE INTERACTION WITH ACTIVIN RECEPTOR IIB., PMID:27502274
Proteomic analysis of the effects of CSF-1 and IL-1α on dental follicle cells., PMID:27484316
RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms., PMID:27460990
Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome., PMID:27076615
High expression of Rab3D predicts poor prognosis and associates with tumor progression in colorectal cancer., PMID:27046094
For research use only. Not for human or drug use.
