Catalog No.
YHF80101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser105-Lys186
Predicted molecular weight
22.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P98177
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Forkhead box protein O4, Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7
The Effect of FSH-Induced Nuclear Exclusion of FOXO3/4 on Granulosa Cell Proliferation and Apoptosis of Hen Ovarian Follicles., PMID:40428322
Structural plasticity of the FOXO-DBD:p53-TAD interaction., PMID:40425537
Cationic microbubbles loading shFOXO4/SDF1 rejuvenate the aged heart and alleviate myocardial ischemia-reperfusion injury in the elderly., PMID:40414465
FoxO4 reduces the damage and mechanism of PEDV-infected IPEC-J2 cells through the NF-κB/MLCK pathway., PMID:40398348
FOXOs and their roles in acute and chronic neurological disorders., PMID:40260403
High-Grade Uterine Sarcoma: First Report of a MEIS2::FOXO4 Fusion., PMID:40249092
Decoding Proteomic cross-talk between hypobaric and normobaric hypoxia: Integrative analysis of oxidative stress, cytoskeleton remodeling, and inflammatory pathways., PMID:40187642
Gene expression profile in ulcerative colitis patients: FOXO4, ALDOB, SLC26A3, SOD2 genes as potential biomarkers., PMID:40153227
ACAA2 Protects Against Cardiac Dysfunction and Lipid Peroxidation in Renal Insufficiency with the Treatment of S-Nitroso-L-Cysteine., PMID:40149900
FOXO4-SP6 axis controls surface epithelium commitment by mediating epigenomic remodeling., PMID:40086444
EWSR1::CREM Fusion in a Pediatric Patient With Testicular Leydig Cell Tumor., PMID:40072299
FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation., PMID:39994346
Effect of Cardamine violifolia on muscle protein degradation and anti-oxidative capacity in weaned piglets after Lipopolysaccharide challenge., PMID:39967238
Evidence for Multiple Independent Expansions of Fox Gene Families Within Flatworms., PMID:39825915
The link of FOXO1 and FOXO4 transcription factors to development of the lens., PMID:39797725
Punicalagin inhibits excessive autophagy and improves cerebral function in neonatal rats with hypoxia-ischemia brain injury by regulating AKT-FOXO4., PMID:39756314
Helicobacter Pylori-induced BRD2 m6A modification sensitizes gastric cancer cells to chemotherapy by breaking FLIP/Caspase-8 homeostasis., PMID:39744419
Transcriptome analysis reveals the genetic basis underlying the formation and seasonal changes of nuptial pads in Rana chensinensis., PMID:39736519
Antiviral activity of HuaganJiedu decoction (HGJDD) against hepatitis B virus (HBV) through FOXO4/ERK/HNF4α signal pathway., PMID:39701219
GLI1::FOXO4-rearranged kidney tumors: a potentially distinct renal subtype within the spectrum of GLI1-altered tumors?, PMID:39688667
Pseudokinase STK40 promotes TH1 and TH17 cell differentiation by targeting FOXO transcription factors., PMID:39565845
Immunocytochemistry-Based Detection of FOXO Isoforms in Human Cancer and Fibroblasts., PMID:39565588
Measuring FOXO Activity by Using qPCR-Based Expression Analysis of FOXO Target Genes., PMID:39565576
FOXO Transcription Factors: A Brief Overview., PMID:39565573
FoxO1 signaling in B cell malignancies and its therapeutic targeting., PMID:39533662
NMR investigation of FOXO4-DNA interaction for discriminating target and non-target DNA sequences., PMID:39487330
Transcriptome Analysis Reveals the Early Development in Subcutaneous Adipose Tissue of Laiwu Piglets., PMID:39457885
Nuclear DUX4 immunohistochemistry is a highly sensitive and specific marker for the presence of CIC::DUX4 fusion in CIC-rearranged sarcomas: a study of 48 molecularly confirmed cases., PMID:39381843
FOXO4 suppresses cisplatin resistance of triple-negative breast cancer by inhibiting autophagy., PMID:39154963
POU5F1B is responsible for the acquired resistance to dabrafenib in papillary thyroid cancer cells with the BRAF V600E mutation., PMID:39136897
Downregulation of 4-HNE and FOXO4 collaboratively promotes NSCLC cell migration and tumor growth., PMID:39085238
FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells., PMID:39025385
Follicular fluid HD-sevs-mir-128-3p is a key molecule in regulating bovine granulosa cells autophagy., PMID:38954995
Identification of angiogenesis-related genes and molecular subtypes for psoriasis based on random forest algorithm., PMID:38938103
CIC::NUTM1 sarcomas occurred in soft tissues of upper limbs : a rare case report and literature review., PMID:38851744
Unravelling the molecular mechanistic pathway underlying the anticancer effects of kaempferol in colorectal cancer: a reverse pharmacology network approach., PMID:38795259
Immunohistochemical Investigation into Protein Expression Patterns of FOXO4, IRF8 and LEF1 in Canine Osteosarcoma., PMID:38792023
Radiation-induced upregulation of FGL1 promotes esophageal squamous cell carcinoma metastasis via IMPDH1., PMID:38702629
Ribosomal S6 kinase 2-forkhead box protein O4 signaling pathway plays an essential role in melanogenesis., PMID:38658799
Multi-omics technologies and molecular biomarkers in brain tumor-related epilepsy., PMID:38641945
Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway., PMID:38566039
Transcriptome Analysis of miRNA and mRNA in Porcine Skeletal Muscle following Glaesserella parasuis Challenge., PMID:38540418
FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation., PMID:38519029
Heterogeneous nuclear ribonucleoprotein A2/B1 promotes myocardial fibrosis by regulating the miR-221-3p/FOXO4-mediated inflammation., PMID:38468493
Knockdown of FOXO4 protects against OGD/R‑induced cerebral microvascular endothelial cell injury and regulates the AMPK/Nrf2/HO‑1 pathway through transcriptional activation of CTRP6., PMID:38313581
Bioinformatics procedure for investigating senolytic (anti-aging) agents: A digital signal processing technique., PMID:38239718
Isotopic Depletion Increases the Spatial Resolution of FPOP Top-Down Mass Spectrometry Analysis., PMID:38226459
Maternal PM2.5 exposure is associated with preterm birth and gestational diabetes mellitus, and mitochondrial OXPHOS dysfunction in cord blood., PMID:38200189
Resveratrol directly suppresses proteolysis possibly via PKA/CREB signaling in denervated rat skeletal muscle., PMID:38055559
CBP-mediated FOXO4 acetylation facilitates postmenopausal osteoporosis (PMO) progression through the inhibition of the Wnt/β-catenin signaling pathway., PMID:38037460
For research use only. Not for human or drug use.
