Catalog No.
YVV00804
Expression system
E. coli
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Protein length
Thr247-Ala419
Predicted molecular weight
22.41 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0DTC9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N, SARS-CoV-2
Convergent evolution in nucleocapsid facilitated SARS-CoV-2 adaptation for human infection., PMID:40503915
Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation., PMID:40503686
Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites., PMID:40501555
An efficient strategy for producing RNA-free Nucleocapsid protein of SARS-CoV-2 for biochemical and structural investigations., PMID:40490992
The effect of early COVID-19 treatment with convalescent plasma on antibody responses to SARS-CoV-2., PMID:40488473
SARS-CoV-2 N protein interacts with Nav1.7 to promote pathological pain., PMID:40488276
Single-particle quantification of SARS-CoV-2 virus-like particles using flow virometry., PMID:40483334
Bats from an area of the Colombian Caribbean reveal the circulation of Alphacoronavirus., PMID:40476071
Seroprevalence Trends of Antibodies to SARS-CoV-2 in South Korea, 2021-2022: A Repeated Cross-Sectional Study., PMID:40462400
SARS-CoV-2-specific humoral immunity in a Norwegian cohort between 2020 and 2023., PMID:40462062
Wastewater dataset on the SARS-CoV-2 sublineages circulating in Central Arkansas, USA, post-COVID-19 pandemic., PMID:40461497
SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity., PMID:40451965
The Overlooked Nucleocapsid Response: A Cohort Study of SARS-CoV-2 Vaccines in Brazil., PMID:40430765
Intrinsic Factors Behind Long COVID: VI. Combined Impact of G3BPs and SARS-CoV-2 Nucleocapsid Protein on the Viral Persistence and Long COVID., PMID:40415285
SERS-based lateral flow immunoassay for rapid and sensitive sensing of nucleocapsid protein toward SARS-CoV-2 screening in clinical samples., PMID:40409906
ELV-N34, RvD6-Isomer, or NPD1 Halt Replication of SARS-CoV-2 Omicron BA.5 Virus in Human Lung and Nasal Cells., PMID:40407038
Lymphocyte Subsets in Covid-19 Saudi Patients: Infection Caused Significant Reduction in Peripheral Blood Lymphocyte Subset., PMID:40387754
Plasmonic coffee-ring biosensing for AI-assisted point-of-care diagnostics., PMID:40382337
Phosphorylation Changes SARS-CoV-2 Nucleocapsid Protein's Structural Dynamics and Its Interaction With RNA., PMID:40375582
Natural product sennoside B disrupts liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein by inhibiting its RNA-binding activity., PMID:40371698
Development of monoclonal antibodies against SARS-CoV-2 nucleocapsid protein for COVID-19 antigen detection., PMID:40361217
Coupling of SARS-CoV-2 to Amyloid Fibrils and Liquid-Liquid Phase Separation., PMID:40353409
Designing a multi-epitope universal vaccine for concurrent infections of SARS-CoV-2 and influenza viruses using an immunoinformatics approach., PMID:40348967
Transfer of SARS-CoV-2 nucleocapsid protein to uninfected epithelial cells induces antibody-mediated complement deposition., PMID:40343796
SARS-CoV-2 N protein interacts with SLC7A11 to cause ferroptosis in acute lung injury., PMID:40342111
Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with lung infection and tissue-damage biomarkers., PMID:40339608
SARS-CoV-2 N protein induces hypokalemia in acute kidney injury mice via ENaC-dependent mechanism., PMID:40336195
PBS-DLS: A Novel Ultrasensitive Dynamic Light Scattering Immunoassay., PMID:40327829
High-resolution structure reveals enhanced 14-3-3 binding by a mutant SARS-CoV-2 nucleoprotein variant with improved replicative fitness., PMID:40318379
Ultra-sensitive heterojunction double gate BioTFET device for SARS-CoV-2 biomolecules detection., PMID:40307462
No Evidence of SARS-CoV-2 Infection in Urban Wildlife of Hokkaido, Japan., PMID:40303042
Variant mutation G215C in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation., PMID:40299982
SARS-CoV-2 N protein and anti-spike serologies: insights into COVID-19 disease severity and mortality-a secondary analysis of the ACTIV-1 trial., PMID:40297751
The Clinical and Laboratory Landscape of COVID-19 During the Initial Period of the Pandemic and at the Beginning of the Omicron Era., PMID:40284924
Nuclear shuttling of CDC4 mediated broad-spectrum antiviral activity against diverse coronaviruses., PMID:40260685
Identification and Characterization of a Novel Protein-Protein Interaction Among SARS-CoV-2 Nucleocapsid, Host SFPQ, and hnRNP U and Its Potential Role in Virus Replication., PMID:40259455
SARS-CoV-2 nucleocapsid protein induces a Mincle-dependent macrophage inflammatory response in acute kidney injury., PMID:40244324
Deep Learning-Based Comparative Prediction and Functional Analysis of Intrinsically Disordered Regions in SARS-CoV-2., PMID:40244295
Developing Zika virus-transduced hACE2 expression models for severe acute respiratory syndrome coronavirus 2 infection in vitro and in vivo., PMID:40239870
Construction and immunogenicity analysis of a recombinant baculovirus targeting the N protein of SARS-CoV-2., PMID:40237823
CLIA immunoassay as an alternative and accurate method to detect Sars-Cov-2 antigen compared to ELISA., PMID:40220581
Optimization of A549 Cell Transfection Efficiency with a Plasmid Encoding the N-Protein of the SARS-CoV-2 Virus., PMID:40216710
Pushing the Limits of Lateral Flow Immunoassay by Digital SERS for the Ultralow Detection of SARS-CoV-2 Virus., PMID:40213455
DeepATsers: a deep learning framework for one-pot SERS biosensor to detect SARS-CoV-2 virus., PMID:40210912
Assessment of genetic diversity, tissue tropism, and antigenic properties of Grimsö betacoronavirus in Swedish bank voles (Clethrionomys glareolus)., PMID:40206840
Development of an ELISA Test with High Diagnostic Accuracy for SARS-COV-2 Using Recombinant Nucleocapsid Protein Expressed in E. coli., PMID:40193039
Targeting USP22 to promote K63-linked ubiquitination and degradation of SARS-CoV-2 nucleocapsid protein., PMID:40183543
Rapid Detection of SARS-CoV-2 in Clinical Samples Combining a Paper-Based Immunoassay With SERS-Based Read out and Machine Learning., PMID:40156372
Detection of IgG Antibodies Against COVID-19 N-Protein by Hybrid Graphene-Nanorod Sensor., PMID:40136961
Nucleocapsid-directed antibody testing is unsuitable to estimate hybrid immunity against SARS-CoV-2, a longitudinal cross-border study in the Meuse-Rhine Euroregion., PMID:40132351