Catalog No.
EHK85401
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Glu33-Cys220
Predicted molecular weight
24.46 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H6X2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Anthrax toxin receptor 1, Tumor endothelial marker 8, ANTXR1, ATR, TEM8
CALCR interaction with ANTXR1 drives gastric tumor growth and metastasis via AKT signaling pathway., PMID:40195530
Association of the ADRB2 rs1042714 variant with retinopathy of prematurity highlights the importance of the renin-angiotensin-aldosterone system., PMID:40175432
Modelling of miRNA-mRNA Network to Identify Gene Signatures with Diagnostic and Prognostic Value in Gastric Cancer: Evidence from In-Silico and In-Vitro Studies., PMID:39995653
Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer., PMID:39917181
DNA Methylation in Recurrent Glioblastomas: Increased TEM8 Expression Activates the Src/PI3K/AKT/GSK-3β/B-Catenin Pathway., PMID:39191501
GAPO syndrome: a novel variant in ANTXR1 gene., PMID:38691016
ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder., PMID:38653789
Distribution of TGFBI variants in patients with early onset glaucoma., PMID:38577561
Prenatal onset GAPO syndrome with a novel ANTXR1 variant in an Indian child: Expansion of the phenotype & literature review., PMID:38423276
Mechanical strain regulates osteogenesis via Antxr1/LncRNA H19/Wnt/β-catenin axis., PMID:38358001
Residual ANTXR1+ myofibroblasts after chemotherapy inhibit anti-tumor immunity via YAP1 signaling pathway., PMID:38346978
Whole-genome resequencing of major populations revealed domestication-related genes in yaks., PMID:38233755
TEM8 in Oncogenesis: Protein Biology, Pre-Clinical Agents, and Clinical Rationale., PMID:37998358
Depleting ANTXR1 suppresses glioma growth via deactivating PI3K/AKT pathway., PMID:37974357
Correlations between Multiple SNPs and HbF Levels in β-Thalassemia Carriers., PMID:37702677
Updated Clinical Perspectives and Challenges of Chimeric Antigen Receptor-T Cell Therapy in Colorectal Cancer and Invasive Breast Cancer., PMID:37566162
An integrative analysis of the tumor suppressors and oncogenes from sexual dimorphism and gene expression alteration features in thyroid cancer., PMID:37355885
Two siblings with GAPO syndrome: Ophthalmic presentation and histopathologic findings., PMID:36748830
Hemangioma-related gene polymorphisms in the pathogenesis of intraventricular hemorrhage in preterm infants., PMID:36656337
ANTXR1 as a potential sensor of extracellular mechanical cues., PMID:36638946
Cancer cell survival depends on collagen uptake into tumor-associated stroma., PMID:36400786
Gene mutations and chromosomal abnormalities in syndromes with tooth agenesis., PMID:36219525
Two siblings with GAPO syndrome: a novel missense variant in ANTXR1., PMID:36094357
ANTXR1 Regulates Erythroid Cell Proliferation and Differentiation through wnt/β-Catenin Signaling Pathway In Vitro and in Hematopoietic Stem Cell., PMID:36065334
Transmembrane Protein ANTXR1 Regulates γ-Globin Expression by Targeting the Wnt/β-Catenin Signaling Pathway., PMID:35942209
Transcriptome and genome sequencing investigating the molecular characteristics of patients with varicocele infertility., PMID:35922383
Serum Proteomic Analysis by Tandem Mass Tag-Based Quantitative Proteomics in Pediatric Obstructive Sleep Apnea., PMID:35480887
Genetic susceptibility to patient-reported xerostomia among long-term oropharyngeal cancer survivors., PMID:35459784
Discriminating Potential Genetic Markers for Complete Response and Non-Complete Response Patients to Neoadjuvant Chemotherapy with Locally Advanced Rectal Cancer., PMID:35409691
Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection., PMID:35322150
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis., PMID:35212873
ANTXR1 as a potential prognostic biomarker for hepatitis B virus-related hepatocellular carcinoma identified by a weighted gene correlation network analysis., PMID:35070431
Changes in mechanical properties of adipose tissue after bariatric surgery driven by extracellular matrix remodelling and neovascularization are associated with metabolic improvements., PMID:35007786
miR-381-3p Involves in Glioma Progression by Suppressing Tumor-Promoter Factor ANTXR1., PMID:34956398
Identification of ITPR1 as a Hub Gene of Group 3 Medulloblastoma and Coregulated Genes with Potential Prognostic Values., PMID:34822110
Quantitative Proteomics Analysis of Differentially Expressed Proteins in Serum of Former Uranium Miners by Isobaric Tags for the Relative and Absolute Quantitation., PMID:34819815
Genetics of ovarian insufficiency and defects of folliculogenesis., PMID:34794894
N-Myc promotes angiogenesis and therapeutic resistance of prostate cancer by TEM8., PMID:34523032
Dental Management of Siblings with GAPO Syndrome., PMID:34321146
Overexpression of tumor endothelial marker 8 protein predicts poor prognosis in angiosarcoma., PMID:34289166
TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer., PMID:34285210
Targeted silencing of TEM8 suppresses non‑small cell lung cancer tumor growth via the ERK/Bcl‑2 signaling pathway., PMID:34165155
N-Linked Glycosylation on Anthrax Toxin Receptor 1 Is Essential for Seneca Valley Virus Infection., PMID:33924774
Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling., PMID:33893326
Latest therapeutic target for gastric cancer: Anthrax toxin receptor 1., PMID:33889273
Infectious recombinant Senecavirus A expressing novel reporter proteins., PMID:33660038
Fetal hemoglobin in sickle cell anemia., PMID:32808012
Anthrax Edema and Lethal Toxins Differentially Target Human Lung and Blood Phagocytes., PMID:32698436
Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis., PMID:32244499
The relationship between TEM8 and early diagnosis and prognosis of lung cancer., PMID:32166929
For research use only. Not for human or drug use.
