Catalog No.
EHK84901
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ile488
Predicted molecular weight
81.37 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y561
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Low-density lipoprotein receptor-related protein 12, LDLR-related protein 12, LRP-12, Suppressor of tumorigenicity 7 protein, LRP12, ST7
Potential therapeutic targets for deep vein thrombosis: A proteome-wide Mendelian randomization study., PMID:40462713
Therapeutic targets for venous thromboemblism: proteome-wide mendelian randomization and colocalization analyses., PMID:40420090
A bioinformatic approach to characterize the vitellogenin receptor and the low density lipoprotein receptor superfamily in the newt Cynops orientalis., PMID:39870874
Linking LRP12 CGG repeat expansion to inherited peripheral neuropathy., PMID:39013564
Short tandem repeat expansions in LRP12 are absent in cohorts of familial and sporadic amyotrophic lateral sclerosis patients of European ancestry., PMID:38726482
Low-density lipoprotein receptor-related protein 5/6 promotes endometrial cancer progression and cancer cell immune escape., PMID:38528715
Bioinformatic analysis of related immune cell infiltration and key genes in the progression of osteonecrosis of the femoral head., PMID:38283345
Proteomic insights into modifiable risk of venous thromboembolism and cardiovascular comorbidities., PMID:38029854
CGG repeat expansion in LRP12 in amyotrophic lateral sclerosis., PMID:37339631
LRP12 is an endogenous transmembrane inactivator of α4 integrins., PMID:37330909
Lipoprotein receptors in ovary of eel, Anguilla australis: molecular characterisation of putative vitellogenin receptors., PMID:36648592
Mining of transcriptome identifies CD109 and LRP12 as possible biomarkers and deregulation mechanism of T cell receptor pathway in Acute Myeloid Leukemia., PMID:36299526
Genomic characteristics of two breast malignant phyllodes tumors during pregnancy and lactation identified through whole-exome sequencing., PMID:36271373
Expanded clinical spectrum of oculopharyngodistal myopathy type 1., PMID:36052448
Oculopharyngodistal myopathy., PMID:35942670
GGC Repeat Expansion of RILPL1 is Associated with Oculopharyngodistal Myopathy., PMID:35700120
Gene expression signatures in PCB-exposed Slovak children in relation to their environmental exposures and socio-physical characteristics., PMID:35420343
Oculopharyngodistal myopathy with CGG repeat expansions in GIPC1: the first report from southwestern China., PMID:35314910
Synovial mesenchymal stem cell-derived extracellular vesicles alleviate chondrocyte damage during osteoarthritis through microRNA-130b-3p-mediated inhibition of the LRP12/AKT/β-catenin axis., PMID:35174753
GIPC1 CGG Repeat Expansion Is Associated with Movement Disorders., PMID:35152460
The CGG repeat expansion in RILPL1 is associated with oculopharyngodistal myopathy type 4., PMID:35148830
NOTCH2NLC-related disorders: the widening spectrum and genotype-phenotype correlation., PMID:34675123
Neuropathy/intranuclear inclusion bodies in oculopharyngodistal myopathy: A case report., PMID:34466670
Clinicopathologic Features of Oculopharyngodistal Myopathy With LRP12 CGG Repeat Expansions Compared With Other Oculopharyngodistal Myopathy Subtypes., PMID:34047774
The GGC repeat expansion in NOTCH2NLC is associated with oculopharyngodistal myopathy type 3., PMID:33693509
5' UTR CGG repeat expansion in GIPC1 is associated with oculopharyngodistal myopathy., PMID:33374016
CGG expansion in NOTCH2NLC is associated with oculopharyngodistal myopathy with neurological manifestations., PMID:33239111
Spatial confinement of receptor activity by tyrosine phosphatase during directional cell migration., PMID:32513699
Oculopharyngodistal myopathy with coexisting histology of systemic neuronal intranuclear inclusion disease: Clinicopathologic features of an autopsied patient harboring CGG repeat expansions in LRP12., PMID:32493488
Noncoding CGG repeat expansions in neuronal intranuclear inclusion disease, oculopharyngodistal myopathy and an overlapping disease., PMID:31332380
Hypolipidemic effect of novel 2,5-bis(4-hydroxybenzylidenamino)-1,3,4-thiadiazole as potential peroxisome proliferation-activated receptor-α agonist in acute hyperlipidemic rat model., PMID:30905023
Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing., PMID:30390000
Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance., PMID:30029672
Identification of pathways and genes associated with synovitis in osteoarthritis using bioinformatics analyses., PMID:29968759
PCB exposure and potential future cancer incidence in Slovak children: an assessment from molecular finger printing by Ingenuity Pathway Analysis (IPA®) derived from experimental and epidemiological investigations., PMID:29143255
Functional Coordination of WAVE and WASP in C. elegans Neuroblast Migration., PMID:27780040
Abundance of LRP12 C-rs9694676 allelic promoter variant in epilepsy-associated gangliogliomas., PMID:27142828
LRP12 silencing during brain development results in cortical dyslamination and seizure sensitization., PMID:26639854
DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma., PMID:25414181
A gene panel, including LRP12, is frequently hypermethylated in major types of B-cell lymphoma., PMID:25226156
Association analysis with lipid traits of 2 candidate genes (LRP12 and TRIB1) mapping to a SSC4 QTL for serum triglyceride concentration in pigs., PMID:23408821
Do GGA adaptors bind internal DXXLL motifs?, PMID:22762444
Lrp12/Mig13a reveals changing patterns of preplate neuronal polarity during corticogenesis that are absent in reeler mutant mice., PMID:20439316
Low Density Lipoprotein Receptor-Related Protein and Apolipoprotein E Expression is Altered in Schizophrenia., PMID:21423430
Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway., PMID:16650524
The low-density lipoprotein receptor-related protein 1 is a mitogenic receptor for lactoferrin in osteoblastic cells., PMID:15178744
Overexpression of LRP12, a gene contained within an 8q22 amplicon identified by high-resolution array CGH analysis of oral squamous cell carcinomas., PMID:14676824
ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways., PMID:12809483
For research use only. Not for human or drug use.
