Catalog No.
EHE95301
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ile28-Gly230
Predicted molecular weight
25.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52799
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5, LERK-5, HTK ligand, HTK-L, EFNB2, EPLG5, HTKL, LERK5
Multi-omic analyses of the development of obesity-related depression linked to the gut microbe Anaerotruncus colihominis and its metabolite glutamate., PMID:40274437
A Disintegrin and Metalloproteinase 10 Regulates Ephrin B2-Mediated Endothelial Cell Sprouting and Ischemic Retinopathy., PMID:40252970
Exploring the causal relationship between serum EFNB2 levels and epilepsy: a bidirectional Mendelian randomization and co-localization analysis., PMID:40045230
Multifaceted analysis of noncoding and coding de novo variants implicates NOTCH signaling pathway in tetralogy of Fallot in Chinese population., PMID:39921258
Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers., PMID:39819837
Upregulation of ABLIM1 Differentiates Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma and Both Colorectal and Pancreatic Adenocarcinoma Liver Metastases., PMID:39766812
EphrinB2-mediated CDK5/ISL1 pathway enhances cardiac lymphangiogenesis and alleviates ischemic injury by resolving post-MI inflammation., PMID:39557830
Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC., PMID:39489818
Dihydroartemisinin Modulates Prostate Cancer Progression by Regulating Multiple Genes via the Transcription Factor NR2F2., PMID:39364872
Circadian system disorder induced by aberrantly activated EFNB2-EPHB2 axis leads to facilitated liver metastasis in gastric cancer., PMID:39298082
EphrinB2 in excitatory neurons and astrocytes in the basolateral amygdala controls long-term fear memory formation., PMID:39289586
Deciphering Dormant Cells of Lung Adenocarcinoma: Prognostic Insights from O-glycosylation-Related Tumor Dormancy Genes Using Machine Learning., PMID:39273449
Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis., PMID:39263947
Loss of Zmiz1 in mice leads to impaired cortical development and autistic-like behaviors., PMID:39211117
Inducible deletion of endothelial cell Efnb2 delays capillary regeneration and attenuates myofibre reinnervation following myotoxin injury in mice., PMID:39196901
Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma., PMID:38985143
Predictive value of plasma ephrinB2 levels for amputation risk following endovascular revascularization in peripheral artery disease., PMID:38854794
Ephrin B2 (EFNB2) potentially protects against intervertebral disc degeneration through inhibiting nucleus pulposus cell apoptosis., PMID:38636690
The integrated bioinformatic analysis identifies immune microenvironment-related potential biomarkers for patients with gestational diabetes mellitus., PMID:38449866
Structure-guided mutagenesis of Henipavirus receptor-binding proteins reveals molecular determinants of receptor usage and antibody-binding epitopes., PMID:38426726
Elucidating Hedgehog pathway's role in HNSCC progression: insights from a 6-gene signature., PMID:38409358
Inhibition of Ephrin B2 Reverse Signaling Abolishes Multiple Myeloma Pathogenesis., PMID:38231476
EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS., PMID:38224498
Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes., PMID:38045373
Sequence basis for selectivity of ephrin-B2 ligand for Eph receptors and pathogenic henipavirus G glycoproteins., PMID:37931130
Temporospatial inhibition of Erk signaling is required for lymphatic valve formation., PMID:37691058
Differentiation and molecular characterization of endothelial progenitor and vascular smooth muscle cells from induced pluripotent stem cells., PMID:37645025
Theranostic Potential of EFNB2 for Cetuximab Resistance in Head and Neck Cancer., PMID:37636764
Transcriptional regulation of the mouse EphA4, Ephrin-B2 and Ephrin-A3 genes by the circadian clock machinery., PMID:37551686
Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice., PMID:37381982
EphrinB2 drives osteogenic fate of adult cardiac fibroblasts in a calcium influx dependent manner., PMID:37212547
The Therapeutic Effects of EFNB2-Fc in a Cell Model of Kawasaki Disease., PMID:37111257
Evaluation of the interaction between potent small molecules against the Nipah virus Glycoprotein in Malaysia and Bangladesh strains, accompanied by the human Ephrin-B2 and Ephrin-B3 receptors; a simulation approach., PMID:36808582
Glycoprotein attachment with host cell surface receptor ephrin B2 and B3 in mediating entry of nipah and hendra virus: a computational investigation., PMID:36465097
Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2., PMID:36438491
Adaptive activation of EFNB2/EPHB4 axis promotes post-metastatic growth of colorectal cancer liver metastases by LDLR-mediated cholesterol uptake., PMID:36376513
A synthetic bivalent peptide ligand of EphB4 with potent agonistic activity., PMID:36208510
Electroacupuncture of Baihui and Shenting ameliorates cognitive deficits via Pten/Akt pathway in a rat cerebral ischemia injury model., PMID:36062010
Histone deacetylase 4 inhibition ameliorates the social deficits induced by Ephrin-B2 mutation., PMID:36029930
In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes., PMID:36028553
Identification and validation of four photodynamic therapy related genes inhibiting MAPK and inducing cell cycle alteration in squamous cell carcinoma., PMID:35992777
EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment., PMID:35725568
Proteomic characterization of the natural history of chronic HBV infection revealed by tandem mass tag-based quantitative proteomics approach., PMID:35665232
Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Longissimus dorsi Skeletal Muscle of Shandong Black Cattle and Luxi Cattle., PMID:35651943
Cellular heterogeneity and transcriptomic profiles during intrahepatic cholangiocarcinoma initiation and progression., PMID:35340039
Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting., PMID:35294885
EphrinB2-EphB4 Signaling in Neurooncological Disease., PMID:35163601
Discovery of Potential Antiviral Compounds against Hendra Virus by Targeting Its Receptor-Binding Protein (G) Using Computational Approaches., PMID:35056869
Vasohibin-1 and -2 in pulmonary lymphangioleiomyomatosis (LAM) cells associated with angiogenic and prognostic factors., PMID:35026646
Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK., PMID:34875308
For research use only. Not for human or drug use.
