Catalog No.
EHA42303
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Tyr19-Phe496
Predicted molecular weight
57.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15123
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Angiopoietin-2, ANG-2, ANGPT2
Expression and Predictive Value of Angiopoietin-2 in Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease., PMID:40512521
PLAC8 Expression Regulates Trophoblast Invasion and Conversion into an Endothelial Phenotype (eEVT)., PMID:40508180
An endothelial specific mouse model for the capillary malformation mutation Gnaq p.R183Q., PMID:40498353
Using vascular biomarkers to assess heart failure event risk in hospitalized patients with and without AKI., PMID:40457292
Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology., PMID:40453069
The BMI1-Angiopoietin-2 axis as an independent prognostic factor in colorectal cancer., PMID:40449824
NNMT/1-MNA protects against hepatic ischemia-reperfusion injury through the AKT/FOXO1/ANGPT2/JNK axis., PMID:40404636
IFN-γ-mediated suppression of ANGPT2-Tie2 in endothelial cells facilitates tumor vascular normalization during immunotherapy., PMID:40370455
Tie2 activity in cancer associated myofibroblasts serves as novel target against reprogramming of cancer cells to embryonic-like cell state and associated poor prognosis in oral carcinoma patients., PMID:40349056
Hormone Receptor-Dependent Correlations Between Angiopoietins and VEGF-C in Primary Breast Cancer: Insights Into Lymphangiogenic Biomarkers., PMID:40348609
An analysis of novel endothelial biomarkers to ascertain their role as prognostic indicators in severe COVID-19 illness., PMID:40347504
Understanding the role of vascular stretch on modulation of VWF and ANGPT-2 in continuous flow left ventricular assist device (CF-VAD) patients., PMID:40314578
Non-enzymatic modification of aminophospholipids induces angiogenesis, inflammation, and insulin signaling dysregulation in human renal glomerular endothelial cells in vitro., PMID:40268103
MAPK Signaling and Angiopoietin-2 Contribute to Endothelial Permeability in Capillary Malformations., PMID:40235979
Plasma proteomic biomarkers predict therapeutic responses in advanced biliary tract cancer patients receiving Camrelizumab plus the GEMOX treatment., PMID:40195413
Extracellular Vesicle-Associated Angiopoietin-2 and Cell Migration-Inducing Protein in Lung Cancer Progression and Brain Metastases., PMID:40190907
Extracellular vesicle-packaged GBP2 from macrophages aggravates sepsis-induced acute lung injury by promoting ferroptosis in pulmonary vascular endothelial cells., PMID:40156957
3D culturing as a promising strategy to enhance the angiogenic potential of adipose stem cell-derived secretome: insights into the role of miR-145-5p/ANGPT2 axis., PMID:40155988
FSTL3 promotes colorectal cancer by activating the HIF1 pathway., PMID:40154584
Spatiotemporal transcriptome atlas of developing mouse lung., PMID:40118721
Associations of ANGPT2 expression and its variants (rs1868554 and rs7825407) with multiple myeloma risk and outcome., PMID:40115011
Enhanced prediction of thrombotic events in hospitalized COVID-19 patients with soluble thrombomodulin., PMID:40106444
RBMS3-loss impedes TRIM21-induced ubiquitination of ANGPT2 in an RNA-independent manner and drives sorafenib resistance in hepatocellular carcinoma., PMID:40069332
Cathepsin K cleavage of angiopoietin-2 creates detrimental Tie2 antagonist fragments in sepsis., PMID:40029709
Angiopoietin-2 regulates the phenotypic switch of vascular smooth muscle cells., PMID:40028724
Angiopoietin-2 and endothelial damage associated with viral load in untreated people living with HIV., PMID:40019463
Huayu Tongbi formula attenuates rheumatoid arthritis by inhibiting the HIF1A/VEGFA/ANGPT axis and suppressing angiogenesis., PMID:39978272
Extracellular matrix ligands modulate the endothelial progenitor cell secretome for enhanced angiogenesis., PMID:39954753
Systemic counterregulatory response of angiopoietin-2 after intravitreal injections with faricimab for nAMD., PMID:39920326
Oocyte transcriptomes and follicular fluid proteomics of ovine atretic follicles reveal the underlying mechanisms of oocyte degeneration., PMID:39893388
Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease., PMID:39868232
Exosome-loading miR-205: a two-pronged approach to ocular neovascularization therapy., PMID:39844301
Dynamics of VEGF-А, Аngiopoietin-2 and HIF-1α Levels in Patients with Brain Metastases Treated with Cyberknife Radiosurgery., PMID:39801284
VAMP8 as a biomarker and potential therapeutic target for endothelial cell dysfunction in atherosclerosis., PMID:39800194
Machine Learning-Based Pathomics Model Predicts Angiopoietin-2 Expression and Prognosis in Hepatocellular Carcinoma., PMID:39746507
Plasma inflammatory and angiogenic protein profiling of patients with sickle cell disease., PMID:39743683
Identification of Angiogenesis-Related Gene Signatures and Prediction of Potential Therapeutic Targets in Ulcerative Colitis Using Integrated Bioinformatics., PMID:39741751
Analysis of the aqueous humor before and after the administration of faricimab in patients with nAMD., PMID:39738534
Potential Role of the Tie2/ Angiopoietin System in Hepatitis C Virus- Induced Hepatocellular Carcinoma., PMID:39733402
Angiogenesis-promoting effect of SKP-SC-EVs-derived miRNA-30a-5p in peripheral nerve regeneration by targeting LIF and ANGPT2., PMID:39732166
[Dual inhibition of VEGF-A and angiopoietin-2 in the treatment of neovascular age-related macular degeneration and diabetic macular edema]., PMID:39731242
Changes in Aqueous Angiopoietin-1/2 Concentrations During the Induction Phase of Intravitreal Faricimab Injections for Diabetic Macular Edema., PMID:39723678
Angiopoietin-2 and Mortality Outcomes in End-Stage Renal Disease with Heart Failure as a Comorbidity., PMID:39710933
Emerging clinical evidence of a dual role for Ang-2 and VEGF-A blockade with faricimab in retinal diseases., PMID:39708087
Pan-cancer analysis reveals the prognostic and immunomodulatory potential of super-enhancer-induced ANGPT2 and experimental validation in colorectal cancer., PMID:39695006
Significance of diagnostic and therapeutic potential of serum endothelial and inflammatory biomarkers in defining disease severity of dengue infected patients., PMID:39674822
Angiogenic effects of Type 2 diabetes on the dental pulp., PMID:39652136
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss., PMID:39636449
Endothelial Angpt2 Promotes Adipocyte Progenitor Cells Maturation to Increase Visceral Adipose Tissue Accumulation., PMID:39628006
Angiogenesis in the mature mouse cortex is governed in a regional- and Notch1-dependent manner., PMID:39612246
For research use only. Not for human or drug use.
