Catalog No.
FHK84310
Species reactivity
Human
Host species
Mouse
Isotype
VHH-mFc
Clonality
Monoclonal
Conjugation
Unconjugated
Target
TSLL1, Immunoglobulin superfamily member 4B, Brain immunoglobulin receptor, NECL1, CADM3, Synaptic cell adhesion molecule 3, Cell adhesion molecule 3, IgSF4B, NECL-1, Nectin-like protein 1, TSLC1-like protein 1, SynCAM3, SYNCAM3, IGSF4B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8N126
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1480
Clinical significance of low expression of CADM3 in breast cancer and preliminary exploration of related mechanisms., PMID:38515057
Pseudo-Dystonia and Marked Intrafamilial Variability in CADM3-Related Disease., PMID:37196599
Circ004463 promotes fibroblast proliferation and collagen I synthesis by sponging miR-23b and regulating CADM3/MAP4K4 via activation of AKT/ERK pathways., PMID:36502948
Cataloguing experimentally confirmed 80.7 kb-long ACKR1 haplotypes from the 1000 Genomes Project database., PMID:34039276
A CADM3 variant causes Charcot-Marie-Tooth disease with marked upper limb involvement., PMID:33889941
Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons., PMID:33397712
Undifferentiated pleomorphic sarcomas with PRDM10 fusions have a distinct gene expression profile., PMID:31313299
Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients-immune-related candidate proteins affected by TNF blocking treatment., PMID:30770760
Necl-4/Cadm4 recruits Par-3 to the Schwann cell adaxonal membrane., PMID:30585357
miR-140-5p suppresses retinoblastoma cell proliferation, migration, and invasion by targeting CEMIP and CADM3., PMID:29808799
Cadm3 (Necl-1) interferes with the activation of the PI3 kinase/Akt signaling cascade and inhibits Schwann cell myelination in vitro., PMID:27658374
Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis., PMID:26401960
Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy., PMID:23825401
Synaptic adhesion molecules in Cadm family at the neuromuscular junction., PMID:23505055
Localization of Cadm2a and Cadm3 proteins during development of the zebrafish nervous system., PMID:21456004
Embryonic corneal Schwann cells express some Schwann cell marker mRNAs, but no mature Schwann cell marker proteins., PMID:19387082
Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site., PMID:19062177
Nectin-like molecule 1 is a glycoprotein with a single N-glycosylation site at N290KS which influences its adhesion activity., PMID:18420026
Crystal structure of the V domain of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule., PMID:16467305
Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins., PMID:11536053
For research use only. Not for human or drug use.
