Catalog No.
FHG52910
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
SLC39A6, LIV1, Zrt- and Irt-like protein 6, Zinc transporter ZIP6, ZIP-6, Estrogen-regulated protein LIV-1, Solute carrier family 39 member 6, ZIP6
Concentration
2.87 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13433
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1475
Zinc transporter ZnT5 is associated with epithelial mesenchymal transition via SMAD1 in breast cancer., PMID:39138630
Patritumab deruxtecan in HER2-negative breast cancer: part B results of the window-of-opportunity SOLTI-1805 TOT-HER3 trial and biological determinants of early response., PMID:38992028
Expression of cell surface zinc transporter LIV1 in triple negative breast cancer is an indicator of poor prognosis and therapy failure., PMID:38345361
Prognostic and Predictive Value of LIV1 Expression in Early Breast Cancer and by Molecular Subtype., PMID:36986799
Zinc transporter LIV1: A promising cell surface target for triple negative breast cancer., PMID:36181695
The importance of targeting signalling mechanisms of the SLC39A family of zinc transporters to inhibit endocrine resistant breast cancer., PMID:35591900
Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer., PMID:33782032
The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis., PMID:32797246
Recombinant Expression of Zinc Transporter SLC39A6 and Its Functional Antibody Production., PMID:31009334
SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer., PMID:25253783
LIV-1 promotes prostate cancer epithelial-to-mesenchymal transition and metastasis through HB-EGF shedding and EGFR-mediated ERK signaling., PMID:22110740
Concordant correlation of LIV-1 and E-cadherin expression in human breast cancer cell MCF-7., PMID:18330719