Catalog No.
EHA05601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Trp317
Predicted molecular weight
38.90 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00214
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Galectin-8, Gal-8, LGALS8, Prostate carcinoma tumor antigen 1
Endogenous Galectin-8 protects against Th17 infiltration and fibrosis following acute kidney injury., PMID:40375122
Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion., PMID:40335523
Galectin-8 drives ERK-dependent mitochondrial fragmentation, perinuclear relocation and mitophagy, with metabolic adaptations for cell proliferation., PMID:40209344
CD98hc, a novel of galectin-8 receptor, binds to galectin-8 in an N-glycosylation-dependent manner., PMID:40205944
Author Correction: Nanomolar inhibitor of the galectin-8 N-terminal domain binds via a non-canonical cation-π interaction., PMID:40169923
Nanomolar inhibitor of the galectin-8 N-terminal domain binds via a non-canonical cation-π interaction., PMID:39994474
Galectin-8 and GEL01 as potential adjuvants to enhance the immune response induced by a DNA vaccine against bovine alphaherpesvirus Type-1., PMID:39854916
Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis., PMID:39747459
Vi capsular polysaccharide of Salmonella enterica serovar Typhi disturbs autophagy to increase intracellular survival in macrophages., PMID:39732413
Functional Characterization of Galectin-8 from Golden Pompano Trachinotus ovatus Reveals Its Broad-Spectrum Antimicrobial Activity., PMID:39688731
Expression and Immune Response Profiles in Nile Tilapia (Oreochromis niloticus) and European Sea Bass (Dicentrarchus labrax) During Pathogen Challenge and Infection., PMID:39684540
Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes., PMID:39602307
Impact of mutations in carbohydrate binding sites of tandem-repeat type galectin from Takifugu obscurus on its antimicrobial activity., PMID:39532191
The interaction of Galectin-8 C-terminal domain with cell surface glycoconjugates modulates membrane elasticity to stimulate antigen uptake and presentation to CD4 T cells., PMID:39365278
Galectin-8 Contributes to Human Trophoblast Cell Invasion., PMID:39337581
B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis., PMID:39231945
Unveiling the molecular characteristics and antibacterial activity of tandem-repeat-type Galectin-8 in large yellow croaker (Larimichthys crocea)., PMID:39173981
Enhancement of Anticancer Potential of Artemisinin Derivatives through N-glycosylation., PMID:39136507
Engineered intrinsically fluorescent galectin-8 variants with altered valency, ligand recognition and biological activity., PMID:39094876
Expression of Intracellular Galectin-8 and -9 in Endometrial Cancer., PMID:39000016
Galectin-8 counteracts folic acid-induced acute kidney injury and prevents its transition to fibrosis., PMID:38936192
The role of galectins in mediating the adhesion of circulating cells to vascular endothelium., PMID:38840921
Capsule-deficient group A Streptococcus evades autophagy-mediated killing in macrophages., PMID:38819157
CALCOCO2/NDP52 associates with RAB9 to initiate an antiviral response to hepatitis B virus infection through a lysosomal degradation pathway., PMID:38752371
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis., PMID:38750548
Galectin-8-like isoform X1 mediates antibacterial, antiviral, and antioxidant responses in red-lip mullet (Planiliza haematocheilus) through positive modulation of pro-inflammatory cytokine, chemokine, and enzymatic antioxidant activity., PMID:38636700
Galectin-8 inhibition and functions in immune response and tumor biology., PMID:38613488
Breaking barriers: How modified citrus pectin inhibits galectin-8., PMID:38597504
Galectin-8 modulates human osteoclast activity partly through isoform-specific interactions., PMID:38395460
Association of GAL-8 promoter methylation levels with coronary plaque inflammation., PMID:38246423
Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors., PMID:38232701
Hypoxia-induced galectin-8 maintains stemness in glioma stem cells via autophagy regulation., PMID:38158714
NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway., PMID:38114531
Screening and Identifying Reference Genes for Erythrocyte Production from Cord Blood CD34+ Cells Exposed to Hypoxia., PMID:38011643
Identification of antimicrobial peptide genes from transcriptomes in Mandarin fish (Siniperca chuatsi) and their response to infection with Aeromonas hydrophila., PMID:38006905
Lipid raft interacting galectin 8 regulates primary ciliogenesis., PMID:37997673
Long noncoding RNA LGALS8-AS1 promotes angiogenesis and brain metastases in non-small cell lung cancer., PMID:37716002
Endogenous Galectin-1 Modulates Cell Biological Properties of Immortalized Retinal Pigment Epithelial Cells In Vitro., PMID:37628816
Galectin-9 as a Potential Modulator of Lymphocyte Adhesion to Endothelium via Binding to Blood Group H Glycan., PMID:37627231
A brief history of galectin evolution., PMID:37457740
TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure., PMID:37409490
Linker remodels human Galectin-8 structure and regulates its hemagglutination and pro-apoptotic activity., PMID:37331541
Chiral growth of adherent filopodia., PMID:37301982
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals., PMID:37122453
Whole microbe arrays accurately predict interactions and overall antimicrobial activity of galectin-8 toward distinct strains of Streptococcus pneumoniae., PMID:37005394
Galectins in Equine Placental Disease., PMID:36977257
Long non-coding RNA LGALS8-AS1 facilitates PLAGL2-mediated malignant phenotypes in gastric cancer., PMID:36807469
Galectin-8 involves in arthritic condylar bone loss via podoplanin/AKT/ERK axis-mediated inflammatory lymphangiogenesis., PMID:36702375
Galectinology of Equine Pregnancy., PMID:36611738
Investigation of anti-galectin-8 levels in patients with multiple sclerosis: A consort-clinical study., PMID:36607856
For research use only. Not for human or drug use.
