Catalog No.
YXX12703
Expression system
E. coli
Species
Vibrio vulnificus (strain CMCP6)
Protein length
Gln21-Leu471
Predicted molecular weight
52.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19247
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytolysin, vvhA, VV2_0404
IgM-functionalized biomimetic nanovaccine for immunological activation and bacterial toxin neutralization., PMID:40360045
Prevalence of Flesh-Eating Bacteria (Vibrio Vulnificus) Type A (Environmental) and Type B (Clinical) in Tilapia Fish Samples: Phenotypic and Molecular Characterizations., PMID:40151886
Genome-wide phenotypic profiling of transcription factors and identification of novel targets to control the virulence of Vibrio vulnificus., PMID:39704106
In vivo examination of pathogenicity and virulence in environmentally isolated Vibrio vulnificus., PMID:39041461
Integration of a CRISPR Cas12a-assisted multicolor biosensor and a micropipette tip enables visible point-of-care testing of foodborne Vibrio vulnificus., PMID:37409577
Targeting Virulence Genes Expression in Vibrio vulnificus by Alternative Carbon Sources., PMID:36499602
Biomimetic Nanosponges Enable the Detoxification of Vibrio vulnificus Hemolysin., PMID:35743264
Refining real-time predictions of Vibrio vulnificus concentrations in a tropical urban estuary by incorporating dissolved organic matter dynamics., PMID:35218838
IL-21 Enhances the Immune Protection Induced by the Vibrio vulnificus Hemolysin A Protein., PMID:35129769
Vibrio vulnificus Hemolysin: Biological Activity, Regulation of vvhA Expression, and Role in Pathogenesis., PMID:33193453
Differential expression of vvhA and CPS operon allele 1 genes in Vibrio vulnificus under biofilm and planktonic conditions., PMID:32696279
Exploring the Pathogenic Potential of Vibrio vulnificus Isolated from Seafood Harvested along the Mangaluru Coast, India., PMID:32635463
Nanosphere Loaded with Curcumin Inhibits the Gastrointestinal Cell Death Signaling Pathway Induced by the Foodborne Pathogen Vibrio vulnificus., PMID:32151068
The role of Vibrio vulnificus virulence factors and regulators in its infection-induced sepsis., PMID:31840198
Occurrence and Abundance of Pathogenic Vibrio Species in Raw Oysters at Retail Seafood Markets in Northwestern Mexico., PMID:31724880
Adaptation to host in Vibrio vulnificus, a zoonotic pathogen that causes septicemia in fish and humans., PMID:31206984
Quantitative PCR enumeration of vcgC and 16S rRNA type A and B genes as virulence indicators for environmental and clinical strains of Vibrio vulnificus in Galveston Bay oysters., PMID:31145009
Intestinal epithelial cell apoptosis due to a hemolytic toxin from Vibrio vulnificus and protection by a 36 kDa glycoprotein from Rhus verniciflua Stokes., PMID:30592968
Identification and Validation of an Antivirulence Agent Targeting HlyU-Regulated Virulence in Vibrio vulnificus., PMID:29868508
Vibrio vulnificus RtxA1 Toxin Expression Upon Contact With Host Cells Is RpoS-Dependent., PMID:29600196
Melatonin inhibits apoptotic cell death induced by Vibrio vulnificus VvhA via melatonin receptor 2 coupling with NCF-1., PMID:29352110
Vibrio vulnificus VvhA induces Th1 and Tfh cells to proliferate against Vibrio vulnificus in a mouse model of infection., PMID:28816516
Regulation systems of protease and hemolysin production in Vibrio vulnificus., PMID:28111826
Vibrio vulnificus VvhA induces autophagy-related cell death through the lipid raft-dependent c-Src/NOX signaling pathway., PMID:27250250
Role of the Histone-Like Nucleoid Structuring Protein (H-NS) in the Regulation of Virulence Factor Expression and Stress Response in Vibrio vulnificus., PMID:26699858
Safety and vaccine efficacy of an attenuated Vibrio vulnificus strain with deletions in major cytotoxin genes., PMID:26381905
Evaluation of recombinant leukocidin domain of VvhA exotoxin of Vibrio vulnificus as an effective toxoid in mouse model., PMID:26141623
Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells., PMID:25695598
Genetic characterization of Vibrio vulnificus strains isolated from oyster samples in Mexico., PMID:25651067
Multiplex PCR assays for the detection of Vibrio alginolyticus, Vibrio parahaemolyticus, Vibrio vulnificus, and Vibrio cholerae with an internal amplification control., PMID:24731836
PVv3, a new shuttle vector for gene expression in Vibrio vulnificus., PMID:24362421
Effects of temperature, growth phase and luxO-disruption on regulation systems of toxin production in Vibrio vulnificus strain L-180, a human clinical isolate., PMID:24068537
Regulation of haemolysin (VvhA) production by ferric uptake regulator (Fur) in Vibrio vulnificus: repression of vvhA transcription by Fur and proteolysis of VvhA by Fur-repressive exoproteases., PMID:23560801
Distribution of virulence markers among Vibrio vulnificus isolates of clinical and environmental origin and regional characteristics in Japan., PMID:23383115
Ecology of Vibrio parahaemolyticus and Vibrio vulnificus in the coastal and estuarine waters of Louisiana, Maryland, Mississippi, and Washington (United States)., PMID:22865080
Additive function of Vibrio vulnificus MARTX(Vv) and VvhA cytolysins promotes rapid growth and epithelial tissue necrosis during intestinal infection., PMID:22457618
[Preparation and characterization of monoclonal antibody against Vibrio vulnificus]., PMID:22394637
Vaccination of sex reversed hybrid tilapia (Oreochromis niloticus × O. aureus) with an inactivated Vibrio vulnificus vaccine., PMID:21982852
Functional characterization of EpsC, a component of the type II secretion system, in the pathogenicity of Vibrio vulnificus., PMID:21788383
Regulation of cytotoxicity by quorum-sensing signaling in Vibrio vulnificus is mediated by SmcR, a repressor of hlyU., PMID:21398530
Virulence characteristics of sucrose-fermenting Vibrio vulnificus strains., PMID:20890083
Outer membrane vesicles of Vibrio vulnificus deliver cytolysin-hemolysin VvhA into epithelial cells to induce cytotoxicity., PMID:20682286
A highly sensitive and specific multiplex PCR assay for simultaneous detection of Vibrio cholerae, Vibrio parahaemolyticus and Vibrio vulnificus., PMID:20666989
Multiplex PCR assays for simultaneous detection and characterization of Vibrio vulnificus strains., PMID:20586937
Iron differentially regulates gene expression and extracellular secretion of Vibrio vulnificus cytolysin-hemolysin., PMID:19586415
The extracellular metalloprotease of Vibrio tubiashii directly inhibits its extracellular haemolysin., PMID:19389767
Development of quantitative real-time polymerase chain reaction for the detection of Vibrio vulnificus based on hemolysin (vvhA) coding system., PMID:18837292
Evaluation of a loop-mediated isothermal amplification assay for detecting Vibrio vulnificus in raw oysters., PMID:18564911
Suppression and inactivation of Vibrio vulnificus hemolysin in cirrhotic ascites, a human ex vivo experimental system., PMID:16831209
Swarming differentiation of vibrio vulnificus downregulates the expression of the vvhBA hemolysin gene via the LuxS quorum-sensing system., PMID:16728960
For research use only. Not for human or drug use.
