Catalog No.
YHB86903
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg670-Gly1022
Predicted molecular weight
45.48kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00533
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB
Silencing IFIT3 suppresses the EGFR/VEGF pathway and modulates SOCS1 to attenuate skin fibrosis in systemic sclerosis., PMID:40515878
MiR-106b-5p improving the progression of chronic kidney disease by inhibiting the TGF-β/Smad pathway., PMID:40514734
Association of HER2-low with clinicopathological features in patients with early invasive lobular breast cancer: an international multicentric study., PMID:40514709
Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas., PMID:40514380
Development and Validation of a Knowledge, Attitude, and Practice (KAP) Questionnaire and its utility study towards Nutritional Habits among Non-Dialytic CKD Patients: A Prospective Study., PMID:40513844
Impact of Renal Impairment on the Pharmacodynamic and Pharmacokinetic Profiles of Epaminurad, a Novel Uric Acid Transporter 1 Inhibitor., PMID:40513003
Structural insights into the activation and inhibition of the ADAM17-iRhom2 complex., PMID:40512800
Prognostic impact of HER2-low expression in triple-negative breast cancer of high-grade special histological type and no special type., PMID:40512776
LiGeR-HN phase III trials of petosemtamab + pembrolizumab and petosemtamab monotherapy in recurrent or metastatic HNSCC., PMID:40511820
Variations in Creatinine Generation Among Patients With Glomerular Disease: Evidence From the NEPTUNE and CureGN Studies., PMID:40510610
Cardiovascular and Thromboembolic Events in Children and Adults With Glomerular Disease: Findings From the Cure GlomeruloNephropathy (CureGN) Network., PMID:40510608
Inverse association between remnant cholesterol and risks of atrial fibrillation among patients with type 2 diabetes., PMID:40510480
Association between physiological serum total bilirubin concentrations and the progression of diabetic nephropathy., PMID:40510475
Potential supplementary tumor markers for liquid biopsy in non-small cell lung cancer., PMID:40510243
Knockdown of Claudin-8 (CLDN8) Indicates a Link Between Breast Cancer Cell Sensitivity to Chemotherapeutics and Reveals a Potential Use of CLDN8 as a Molecular Diagnostic and Target for Therapy., PMID:40508219
Potassium Iodide Induces Apoptosis in Salivary Gland Cancer Cells., PMID:40508009
Unraveling Botulinum Neurotoxin A Light-Chain-Induced Signaling Pathways: A Phosphoproteomic Analysis in a Controlled Cellular Model., PMID:40507977
Dihydrocapsaicin Enhances Tumor Necrosis Factor-α-Induced Apoptosis and G1 Cell Cycle Arrest in Human Cervical Cancer Cells Through TAK1-Mediated NF-κB and EGFR Pathways., PMID:40507823
Evaluation of Risk Factors for Kidney Function Decline and Chronic Kidney Disease in Living Kidney Donors., PMID:40507639
Reciprocal Fluctuations in Lipoprotein Lipase, Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1, and Hepatic Triglyceride Lipase Levels in the Peripheral Bloodstream Are Correlated with Insulin Resistance., PMID:40507147
Covalent Recruitment of NEDD4 for Targeted Protein Degradation: Rational Design of Small Molecular Degraders., PMID:40506832
[Research Status and Progress of Third-generation EGFR-TKIs
in Elderly Patients with Non-small Cell Lung Cancer]., PMID:40506487
Therapeutic Outcomes of Osimertinib in EGFR - Mutant Non-Small Cell Lung Cancer With Brain Metastases: Results From a Retrospective Study at Vietnam National Cancer Hospital., PMID:40506044
CYR61 and CTGF mediate the stimulatory effect of amphiregulin on COX-2 expression in human granulosa-lutein cells., PMID:40506006
YiQiChuTan formula (YQCTF) inhibit the progression of non-small cell lung cancer via down-regulating EGFR/ITGB2 signaling: Triangulated evidence from network pharmacology, proteomic profiling, and experimental validation., PMID:40505482
Hereditary breast cancer beyond BRCA: clinicopathological characteristics and long-term outcomes., PMID:40504267
RNF213-Dependent EGFR and HER2 Activation Regulates Specific Downstream Signaling Pathways in Human Cancer Cells., PMID:40503863
Modeling acquired TKI resistance and effective combination therapeutic strategies in murine RET+ lung adenocarcinoma., PMID:40502048
Kasugamycin inhibits melanoma lung metastasis and regulates CHI3L1-driven M2-like tumor-associated macrophage differentiation., PMID:40501604
Impact of age and comorbidities on real-world outcomes in advanced breast cancer patients treated with palbociclib in first line: a nation-wide Danish retrospective study., PMID:40500959
Exploring the Mechanism of Feiyanning formula and its extract Apigenin Against EGFR-TKIs Resistance in Non-Small Cell Lung cancer Based on UPLC-HRMS and Experimental Validation., PMID:40499802
Super-resolution microscopy reveals alterations in clathrin structure in human cancer tissue., PMID:40499781
Dynamic VOC fingerprinting and mechanistic exploration of medicinal edible fungus Inonotus hispidus: A combination of HS-GC-IMS/MS multivariate analysis and network-based pharmacology., PMID:40499502
Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients: The ALBICS AKI Randomized Clinical Trial., PMID:40498523
ERBB2-Low Expression by Race and Ethnicity Among Patients With Triple-Negative Breast Cancer., PMID:40498483
Targeting the Cargo Receptor TMED9 as a Therapeutic Strategy Against Brain Tumors., PMID:40497947
Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway., PMID:40495892
Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation., PMID:40494352
Biomarker-Specific Survival and Medication Cost for Patients With Non-Small Cell Lung Cancer., PMID:40493365
Prevalence and risk factors of chronic kidney disease of unknown etiology in Northeast Thailand., PMID:40493280
Supramolecular Host-Guest Assemblies for Tunable and Modular Lysosome-Targeting Protein Degradation., PMID:40492932
Impaired lung function is associated with elevated blood biomarkers of AD/ADRD: Unraveling the interplay with risk of dementia., PMID:40492085
Association Between the Hemoglobin Glycation Index (HGI) and Risk of Diabetic Nephropathy: A Retrospective Cohort Study., PMID:40491573
RalGAP complexes control secretion and primary cilia in pancreatic disease., PMID:40490362
Amiloride synergizes with EGFR PROTACs and inhibitors to overcome therapeutic resistance in NSCLC., PMID:40489919
Predictive power of tertiary lymphoid structure for prognosis and neoadjuvant chemotherapy response in HER2-positive breast cancer., PMID:40489875
Network pharmacology and molecular docking-based characterization of the mechanisms through which Astragali Radix-Atractylodes macrocephala Koidz herb pair can treat membranous nephropathy., PMID:40489804
An Advanced IVB Lung Adenocarcinoma Patient With KRAS Mutations, Benefited From Camrelizumab Combined With Anti-Angiogenic Agents for Therapy: A Case Report., PMID:40488279
SPDL1 inhibition enhances colorectal cancer progression via epidermal growth factor receptor/extracellular signal-regulated kinase pathways., PMID:40487946
Mechanisms Underlying the Therapeutic Effects of Brucea javanica in Cervical Cancer Treatment Based on Network Pharmacology and Molecular Docking., PMID:40487864
For research use only. Not for human or drug use.
