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InVivoMAb Anti-Human β-tryptase/TPSAB1 Antibody (31A)

Catalog #:   VHH16101 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: Blocking, ELISA
Accession: Q15661
Overview

Catalog No.

VHH16101

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

TPSB1, TPS2, Tryptase I, Tryptase-1, TPSAB1, Tryptase alpha-1, Tryptase alpha/beta-1, TPS1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q15661

Applications

Blocking, ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

31A

Data Image
  • Bioactivity
    Detects Human β-tryptase/TPSAB1 in indirect ELISAs.
  • Western blot
    Various lysates were subjected to SDS PAGE followed by western blot with Human TPSAB1 antibody (VHH16101) at 1μg/ml.

    Lane 1: Human TPSAB1 transfected HEK293 cell lysate
    Lane 2: Non-transfected HEK293 cell lysate

    Second Ab: Goat Anti-Mouse IgG H&L Polyclonal antibody, HRP (PMB96431) at 0.1 μg/mL.

    Predict MW: 31.28 kDa
    Observed MW: 36 kDa
References

Hereditary alpha-tryptasemia - a potential cause of severe anaphylactic reactions and a modifier of mast cell diseases., PMID:40450750

Hereditary α-tryptasemia is Associated With Anaphylaxis to Antibiotics and Monoclonal Antibodies., PMID:40239920

[Indolent systemic mastocytosis : an overview in 2025]., PMID:40176613

The reduction effect on sensitization of sesame protein Ses i 3 of ultrasound-assisted glycation treatment through modulation of T cell differentiation., PMID:40089237

Cold-induced anaphylaxis: new insights into clinical and genetic characteristics., PMID:40061949

Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor Alpha., PMID:40045925

Perioperative anaphylaxis manifesting as cardiac arrest during cardiac surgery., PMID:39741371

Occupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI)., PMID:39659712

Elevated circulating group-2 innate lymphoid cells expressing activation markers and correlated tryptase AB1 levels in active ascariasis., PMID:39524451

Eosinophilic cationic protein and D-Dimer are potential biomarkers to predict response to antihistamines but not to omalizumab in chronic spontaneous urticaria., PMID:39467078

Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601

Unraveling wasp sensitization in a patient with systemic mastocytosis by CAP-inhibition assay., PMID:39278856

Airway tryptase levels inform the lack of clinical efficacy of the tryptase inhibitor MTPS9579A in asthma., PMID:39250147

Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma., PMID:39097197

Clinical features, severity, and immunological changes during venom immunotherapy in children and adults., PMID:38982596

Neuromuscular blocking agent drug challenge: a literature review and protocol proposal with biological evaluation., PMID:38916219

Histochemical and immunohistochemical investigation of the number and localization of mast cells in the feline tongue., PMID:38831730

Test Panel of Hidden Allergens for "Idiopathic Anaphylaxis" Reveals Wheat Allergy Dependent on Augmentation Factors as Common Final Diagnosis., PMID:38821438

Interplay of clinical biomarkers in allergic asthma diagnosis and severity: A case-control study., PMID:38814233

Perioperative anaphylaxis: updates on pathophysiology., PMID:38743470

Protective role of protease-activated receptor-2 in anaphylaxis model mice., PMID:38635782

Luteolin Is More Potent than Cromolyn in Their Ability to Inhibit Mediator Release from Cultured Human Mast Cells., PMID:38588651

Characterization of the potential allergenicity of enzymatically hydrolyzed casein in Balb/c mouse model., PMID:38563099

Prevention of Anaphylaxis Episodes in Idiopathic Anaphylaxis by Omalizumab., PMID:38527445

Anti-allergic effect of vitamin C through inhibiting degranulation and regulating TH1/TH2 cell polarization., PMID:38415860

Expression of mast cell tryptase and immunoglobulin E is increased in cutaneous photodamage: implications for carcinogenesis., PMID:38291602

Circulating microbiome analysis in patients with perioperative anaphylaxis., PMID:38274796

The Clinical Features of Hereditary Alpha-Tryptasemia—Implications for Interdisciplinary Practice., PMID:38260947

Comparative analyses of various IgE-mediated and non-IgE-mediated inducers of mast cell degranulation for in vitro study., PMID:38001385

TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase., PMID:37963864

Diagnosis and treatment of Hymenoptera venom allergy: S2k Guideline of the German Society of Allergology and Clinical Immunology (DGAKI) in collaboration with the Arbeitsgemeinschaft für Berufs- und Umweltdermatologie e.V. (ABD), the Medical Association of German Allergologists (AeDA), the German Society of Dermatology (DDG), the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNOKC), the German Society of Pediatrics and Adolescent Medicine (DGKJ), the Society for Pediatric Allergy and Environmental Medicine (GPA), German Respiratory Society (DGP), and the Austrian Society for Allergy and Immunology (ÖGAI)., PMID:37854067

Update on Mast Cell Proteases as Drug Targets., PMID:37758413

Altered interictal serum histamine and immunoglobulin E but unchanged tryptase levels in individuals with episodic and chronic migraine., PMID:37226451

Postmortem Biochemistry and Immunohistochemistry in Anaphylactic Death Due to Hymenoptera Sting: A Forensic Case Report., PMID:37174160

Ten-year outcomes of Perioperative Anaphylaxis Workup Study in Hong Kong (PAWS-HK): Performance of diagnostic modalities., PMID:36842494

A mechanistic PK/PD model to enable dose selection of the potent anti-tryptase antibody (MTPS9579A) in patients with moderate-to-severe asthma., PMID:36755366

Severe perioperative anaphylaxis: Incidence in a tertiary hospital in Spain over a 20-year period. A historical cohort study., PMID:36621573

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels., PMID:36514263

Causes and Diagnostic Usefulness of Tryptase Measurements for Anaphylaxis in a Korean Tertiary Care General Hospital., PMID:36444545

Anti-KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria., PMID:36385701

Interleukin-6 and cytokine release syndrome: A new understanding in drug hypersensitivity reactions., PMID:36343890

Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment., PMID:36211437

Diagnostic value of a medical algorithm for investigation of perioperative hypersensitivity reactions., PMID:36136057

Systematic comparisons of various markers for mast cell activation in RBL-2H3 cells., PMID:36125550

Agreement of a clinical scoring system with allergic anaphylaxis in suspected perioperative hypersensitivity reactions: prospective validation of a new tool., PMID:36085094

Probiotics in Experimental Ulcerative Colitis: Mast Cell Density and Neuronal Hypertrophy., PMID:35946877

Autoantibodies to IgE can induce the release of proinflammatory and vasoactive mediators from human cardiac mast cells., PMID:35879625

IgE-mediated anaphylaxis to methylprednisolone succinate in a patient with indolent systemic mastocytosis., PMID:35817697

Global Classification of Mast Cell Activation Disorders: An ICD-10-CM-Adjusted Proposal of the ECNM-AIM Consortium., PMID:35623575

Mast Cell Activation Syndromes: Collegium Internationale Allergologicum Update 2022., PMID:35605594

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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InVivoMAb Anti-Human β-tryptase/TPSAB1 Antibody (31A) [VHH16101]
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