Ficolin-3 Activates Complement and Triggers Necroptosis in Cholangiocarcinoma Cells via the RIPK1/RIPK3/MLKL Signaling Pathway., PMID:40407231
Correlations of the Complement Proteins MASP-2 and MASP-3 With Clinical Severity and Short-Term Outcomes in Primary Membranous Nephropathy Patients., PMID:40294883
Contemporary review of IgA nephropathy., PMID:39188719
Identification and functionalization of thyrotropin receptor antibodies with different antigenic epitopes., PMID:39046281
Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury., PMID:38807149
Safety and efficacy of narsoplimab in pediatric and adult patients with transplant-associated thrombotic microangiopathy: a real-world experience., PMID:38773280
CL-11 circulates in serum as functionally distinct isoforms., PMID:38466278
Compassionate Use Narsoplimab for Severe Refractory Transplantation-Associated Thrombotic Microangiopathy in Children., PMID:38145741
Development and characterization of narsoplimab, a selective MASP-2 inhibitor, for the treatment of lectin-pathway-mediated disorders., PMID:38022610
Clinical advances in immunotherapy for immune-mediated glomerular diseases., PMID:37889398
Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection., PMID:37878754
Evaluation of the significance of complement-related genes mutations in atypical postinfectious glomerulonephritis: a pilot study., PMID:37845399
MAP-2:CD55 chimeric construct effectively modulates complement activation., PMID:37823685
In vaccinated individuals serum bactericidal activity against B meningococci is abrogated by C5 inhibition but not by inhibition of the alternative complement pathway., PMID:37457736
Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice., PMID:37325666
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence., PMID:37191586
Narsoplimab for severe transplant-associated thrombotic microangiopathy., PMID:36915123
Inhibition of the different complement pathways has varying impacts on the serum bactericidal activity and opsonophagocytosis against Haemophilus influenzae type b., PMID:36578495
Significance of Mannan Binding Lectin-Associated Serine Protease 2 in Urinary Extracellular Vesicles in IgA Nephropathy., PMID:36149051
Mannose binding lectin-associated serine protease 2 (MASP2) gene polymorphism and susceptibility to human T-lymphotropic virus type 1 (HTLV-1) infection in blood donors from Mashhad, Iran., PMID:35924689
MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease., PMID:35878790
Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19., PMID:35816998
Low levels of the innate immune system proteins MASP-2 and MAp44 in patients with common variable immunodeficiency., PMID:35673952
Circulating immune-complexes and complement activation through the classical pathway in myeloperoxidase-ANCA-associated glomerulonephritis., PMID:35491890
Narsoplimab, a Mannan-Binding Lectin-Associated Serine Protease-2 Inhibitor, for the Treatment of Adult Hematopoietic Stem-Cell Transplantation-Associated Thrombotic Microangiopathy., PMID:35439028
Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?, PMID:35121432
Alternative Complement Pathway Inhibition Abrogates Pneumococcal Opsonophagocytosis in Vaccine-Naïve, but Not in Vaccinated Individuals., PMID:34707606
Alternative Complement Pathway Inhibition Does Not Abrogate Meningococcal Killing by Serum of Vaccinated Individuals., PMID:34691058
The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?, PMID:34682837
The lectin pathway does not contribute to glomerular injury in the nephrotoxic nephritis model., PMID:34676615
Multiple-Organ Complement Deposition on Vascular Endothelium in COVID-19 Patients., PMID:34440207
Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins., PMID:34290717
MASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19., PMID:33729332
Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections., PMID:33671334
Multi-organ complement deposition in COVID-19 patients., PMID:33442701
Safety, Tolerability and Efficacy of Narsoplimab, a Novel MASP-2 Inhibitor for the Treatment of IgA Nephropathy., PMID:33163724
Targeting complement cascade: an alternative strategy for COVID-19., PMID:33088671
Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab., PMID:32943233
Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19., PMID:32771488
Inhibition of the Lectin Pathway of the Complement System as a Novel Approach in the Management of IgA Vasculitis-Associated Nephritis., PMID:32721954
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti-MASP2 antibody narsoplimab., PMID:32681658
Complement activation is associated with crescent formation in IgA nephropathy., PMID:32300880
Complement Deficiencies Result in Surrogate Pathways of Complement Activation in Novel Polygenic Lupus-like Models of Kidney Injury., PMID:32238460
Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D., PMID:32153567
Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury., PMID:31608060
Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1)., PMID:30323815
Is Early Complement Activation in Renal Transplantation Associated with Later Graft Outcome?, PMID:30286468
Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice., PMID:29892304
Human anti-thrombospondin type 1 domain-containing 7A antibodies induce membranous nephropathy through activation of lectin complement pathway., PMID:29769410
Cardioprotection by an anti-MASP-2 antibody in a murine model of myocardial infarction., PMID:29344374
For research use only. Not for human or drug use.
