Catalog No.
YVV26101
Expression system
E. coli
Species
Canine distemper virus (strain A92-27/4) (CDV)
Protein length
Arg187-Arg597
Predicted molecular weight
48.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q66001
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hemagglutinin glycoprotein, H
Human SLAM-adapted canine distemper virus can enter human peripheral blood mononuclear cells and replicate in mice expressing human SLAM and defective for STAT1 expression., PMID:39981650
Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination., PMID:39046448
A Bacterium-like Particle Vaccine Displaying Envelope Proteins of Canine Distemper Virus Can Induce Immune Responses in Mice and Dogs., PMID:38675892
Immunogenicity and protective efficacy of a novel bacterium-like particle-based vaccine displaying canine distemper virus antigens in mice and dogs., PMID:38456681
The H protein of attenuated canine distemper virus is degraded via endoplasmic reticulum-associated protein degradation., PMID:37483299
Fusion protein and hemagglutinin of canine distemper virus co-induce apoptosis in canine mammary tumor cells., PMID:37249647
Structure and supramolecular organization of the canine distemper virus attachment glycoprotein., PMID:36716368
LRP6 Is a Functional Receptor for Attenuated Canine Distemper Virus., PMID:36645301
Selective SLAM/CD150 receptor-detargeting of canine distemper virus., PMID:35649483
Robust envelope exchange platform for oncolytic measles virus., PMID:35104497
Computational Analysis Reveals a Critical Point Mutation in the N-Terminal Region of the Signaling Lymphocytic Activation Molecule Responsible for the Cross-Species Infection with Canine Distemper Virus., PMID:33652764
MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum., PMID:33534834
Antiviral Screen against Canine Distemper Virus-Induced Membrane Fusion Activity., PMID:33477492
A highly efficient recombinant canarypox virus-based vaccine against canine distemper virus constructed using the CRISPR/Cas9 gene editing method., PMID:33197867
Isolation and molecular characterizations of canine distemper virus from a naturally infected Korean dog using Vero cells expressing dog signaling lymphocyte activation molecule., PMID:33016015
Retargeted and Stealth-Modified Oncolytic Measles Viruses for Systemic Cancer Therapy in Measles Immune Patients., PMID:32847970
Cryo-EM structure of the prefusion state of canine distemper virus fusion protein ectodomain., PMID:32647825
A Bivalent Human Adenovirus Type 5 Vaccine Expressing the Rabies Virus Glycoprotein and Canine Distemper Virus Hemagglutinin Protein Confers Protective Immunity in Mice and Foxes., PMID:32612580
Specificity of Morbillivirus Hemagglutinins to Recognize SLAM of Different Species., PMID:31430904
Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins., PMID:31357579
Fusion and hemagglutinin proteins of canine distemper virus promote osteoclast formation through NF-κB dependent and independent mechanisms., PMID:30880029
Tropism and molecular pathogenesis of canine distemper virus., PMID:30845967
Primary resistance mechanism of the canine distemper virus fusion protein against a small-molecule membrane fusion inhibitor., PMID:30296457
Regulatory Role of the Morbillivirus Attachment Protein Head-to-Stalk Linker Module in Membrane Fusion Triggering., PMID:29997204
Canine Distemper Virus Spread and Transmission to Naive Ferrets: Selective Pressure on Signaling Lymphocyte Activation Molecule-Dependent Entry., PMID:29793948
Inactivated Recombinant Rabies Viruses Displaying Canine Distemper Virus Glycoproteins Induce Protective Immunity against Both Pathogens., PMID:28148801
Measles Virus Fusion Protein: Structure, Function and Inhibition., PMID:27110811
Morbillivirus and henipavirus attachment protein cytoplasmic domains differently affect protein expression, fusion support and particle assembly., PMID:26813519
Efficient generation of vesicular stomatitis virus (VSV)-pseudotypes bearing morbilliviral glycoproteins and their use in quantifying virus neutralising antibodies., PMID:26706278
Canine Distemper Virus Fusion Activation: Critical Role of Residue E123 of CD150/SLAM., PMID:26608324
Sequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion process., PMID:25946112
Canine distemper virus neutralization activity is low in human serum and it is sensitive to an amino acid substitution in the hemagglutinin protein., PMID:25880113
Identification of amino acid substitutions with compensational effects in the attachment protein of canine distemper virus., PMID:24807725
Recent host range expansion of canine distemper virus and variation in its receptor, the signaling lymphocyte activation molecule, in carnivores., PMID:24807184
The V domain of dog PVRL4 (nectin-4) mediates canine distemper virus entry and virus cell-to-cell spread., PMID:24725937
Molecular determinants defining the triggering range of prefusion F complexes of canine distemper virus., PMID:24371057
Membrane-bound SIV envelope trimers are immunogenic in ferrets after intranasal vaccination with a replication-competent canine distemper virus vector., PMID:24074564
Experimental adaptation of wild-type canine distemper virus (CDV) to the human entry receptor CD150., PMID:23554862
Antagonistic pleiotropy and fitness trade-offs reveal specialist and generalist traits in strains of canine distemper virus., PMID:23239996
Canine distemper virus with the intact C protein has the potential to replicate in human epithelial cells by using human nectin4 as a receptor., PMID:23174504
Morbillivirus glycoprotein expression induces ER stress, alters Ca2+ homeostasis and results in the release of vasostatin., PMID:22403712
Canine distemper virus infects canine keratinocytes and immune cells by using overlapping and distinct regions located on one side of the attachment protein., PMID:21849439
Envelope-chimeric entry-targeted measles virus escapes neutralization and achieves oncolysis., PMID:21610701
Canine distemper virus matrix protein influences particle infectivity, particle composition, and envelope distribution in polarized epithelial cells and modulates virulence., PMID:21543493
Canine distemper virus persistence in demyelinating encephalitis by swift intracellular cell-to-cell spread in astrocytes is controlled by the viral attachment protein., PMID:20119836
Canine distemper viruses expressing a hemagglutinin without N-glycans lose virulence but retain immunosuppression., PMID:20042514
Conserved leucine residue in the head region of morbillivirus fusion protein regulates the large conformational change during fusion activity., PMID:19705836
Functional interaction between paramyxovirus fusion and attachment proteins., PMID:18426797
CD9 clustering and formation of microvilli zippers between contacting cells regulates virus-induced cell fusion., PMID:18363777
Synergistic inhibition in cell-cell fusion mediated by the matrix and nucleocapsid protein of canine distemper virus., PMID:17706826
For research use only. Not for human or drug use.
