Catalog No.
YHK83401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly93-Gly431
Predicted molecular weight
39.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96QT4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LTrpC7, LTRPC7, LTrpC-7, TRPM7, Transient receptor potential cation channel subfamily M member 7, CHAK1, Long transient receptor potential channel 7, Channel-kinase 1
Phosphodiesterase 3 inhibitors boost bone outgrowth., PMID:40456620
Mg2+ Supplementation Mitigates Metabolic Deficits Associated With TRPM7 Disruption., PMID:40275767
The kinase domain of TRPM7 interacts with PAK1 and regulates pancreatic cancer cell epithelial-to-mesenchymal transition., PMID:40274768
Placental magnesium transport-related mRNA expression is not associated with serum magnesium in singletons and twins., PMID:40222296
Mg2+ influx mediated by TRPM7 triggers the initiation of muscle stem cell activation., PMID:40184450
Huangqi Guizhi Wuwu Decoction alleviates diabetic cardiovascular autonomic neuropathy via AMPK/TrkA/TRPM7 pathway., PMID:40107475
TRPM6 in murine kidneys-of targets and antibodies., PMID:40025338
Molecular Mechanism of Oil-Infused Silicone Preventing Mussel Biofouling., PMID:39995899
TRPM7 channel activity promotes the pathogenesis of abdominal aortic aneurysms., PMID:39953276
The TRPM7 chanzyme in smooth muscle cells drives abdominal aortic aneurysm in mice., PMID:39953275
Role of TRP Channels in Cancer-Induced Bone Pain., PMID:39940997
A distal convoluted tubule-specific isoform of murine SLC41A3 extrudes magnesium., PMID:39931759
Inhibition of TRPM7 by glutathione decreases oxidant and apoptotic action of cisplatin through the downregulation of Ca2+ and Zn2+ in glioblastoma cells., PMID:39892615
Roles of calcium in ameloblasts during tooth development: A scoping review., PMID:39839572
Transient receptor potential melastatin 7 cation channel, magnesium and cell metabolism in vascular health and disease., PMID:39801180
Discovery of the therapeutic potential of naltriben against glutamate-induced neurotoxicity., PMID:39756586
TRPM7 activity drives human CD4 T-cell activation and differentiation in a magnesium dependent manner., PMID:39677770
Macrophage Dvl2 deficiency promotes NOD1-Driven pyroptosis and exacerbates inflammatory liver injury., PMID:39644526
Roles of Necroptosis, Apoptosis, and Inflammation in Colorectal Carcinogenesis: A Longitudinal Human Study., PMID:39637028
Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation., PMID:39627337
Missense variants in the TRPM7 α-kinase domain are associated with recurrent pediatric acute liver failure., PMID:39621058
TRPM7 contributes to pyroptosis and its involvement in status epilepticus., PMID:39617893
METTL14 Promotes Lipopolysaccharide-Induced Myocardial Damage via m6A-Dependent Stabilization of TRPM7 mRNA., PMID:39617501
Differential regulation of magnesium transporters Slc41, Cnnm and Trpm6-7 in the kidney of salmonids may represent evolutionary adaptations to high salinity environments., PMID:39614204
Expression Profiling Identified TRPM7 and HER2 as Potential Targets for the Combined Treatment of Cancer Cells., PMID:39513908
Identification of Cannabidiolic and Cannabigerolic Acids as MTDL AChE, BuChE, and BACE-1 Inhibitors Against Alzheimer's Disease by In Silico, In Vitro, and In Vivo Studies., PMID:39510547
Mild therapeutic hypothermic protection activates the PI3K/AKT signaling pathway to inhibit TRPM7 and suppress ferroptosis induced by myocardial ischemia‑reperfusion injury., PMID:39364741
Endosomal fusion of pH-dependent enveloped viruses requires ion channel TRPM7., PMID:39353909
Inhibition of the RIP3/MLKL/TRPM7 necroptotic pathway ameliorates diabetes mellitus-induced erectile dysfunction by reducing cell death, fibrosis, and inflammation., PMID:39329120
Exploring therapeutic potential: Targeting TRPM7 in neurodegenerative diseases., PMID:39298812
Hypomagnesaemia leading to parathyroid dysfunction, hypocalcaemia, and hypokalaemia as a complication of long-term treatment with a proton pump inhibitor - a literature review., PMID:39279305
Characterization of intestine-specific TRPM6 knockout C57BL/6 J mice: effects of short-term omeprazole treatment., PMID:39266724
Protective role of TRPM7 knockdown in ulcerative colitis via blocking NLRP3 inflammasome-mediated pyroptosis., PMID:39260818
Effects of long-term magnesium L-threonate supplementation on neuroinflammation, demyelination and blood-brain barrier integrity in mice with neuromyelitis optica spectrum disorder., PMID:39260790
Discovery of selective Orai channel blockers bearing an indazole or a pyrazole scaffold., PMID:39232360
Novel benzoylurea derivative decreases TRPM7 channel function and inhibits cancer cells migration., PMID:39212541
F-actin microfilaments affect the LIPUS-promoted osteogenic differentiation of BMSCs through TRPM7., PMID:39212193
Fentanyl induces analgesic effect through miR-381-3p/TRPM7 when combined with bupivacaine in subarachnoid injection., PMID:39191357
TRPM7 controls skin keratinocyte senescence by targeting intracellular calcium signaling., PMID:39185948
NS8593 inhibits chondrocyte ferroptosis and alleviates cartilage injury in rat adjuvant arthritis through TRPM7 / HO-1 pathway., PMID:39053766
Kdm4a is an activity downregulated barrier to generate engrams for memory separation., PMID:39003305
Role of Piezo2 in Schwann Cell Volume Regulation and Its Impact on Neurotrophic Release Regulation., PMID:38973197
Zebrafish trpm7 mutants show reduced motility in free movement., PMID:38970357
Interaction of NF-κB and FOSL1 drives glioma stemness., PMID:38856747
High Magnesium Promotes the Recovery of Binocular Vision from Amblyopia via TRPM7., PMID:38833201
Emodin Attenuates Sepsis-induced Intestinal Injury by Regulating TRPM7 Expression., PMID:38819184
SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway in hepatocellular carcinoma., PMID:38753154
Genetic Screening of Patients with Sporadic Alzheimer's Disease and Frontotemporal Lobar Degeneration in the Chinese Population., PMID:38701145
Hypoxia-induced TRPM7 promotes glycolytic metabolism and progression in hepatocellular carcinoma., PMID:38677534
Magnesium Ions Promote the Induction of Immunosuppressive Bone Microenvironment and Bone Repair through HIF-1α-TGF-β Axis in Dendritic Cells., PMID:38661278
For research use only. Not for human or drug use.
