Catalog No.
YHE30501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu86-Val411
Predicted molecular weight
40.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P41219
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neurofilament 4, NEF4, PRPH1, Peripherin, PRPH
Peripherin: A Novel Early Diagnostic and Prognostic Plasmatic Biomarker in Amyotrophic Lateral Sclerosis., PMID:40476320
Developmental differentiation of mouse inner ear neuron subpopulations resolved with a peripherin-promoter reporter within the Grm8 locus., PMID:40133378
GABAB Receptor Modulation of Membrane Excitability in Human Pluripotent Stem Cell-Derived Sensory Neurons by Baclofen and α-Conotoxin Vc1.1., PMID:39871624
Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevation., PMID:37862216
Axonal Transport Defect in Gigaxonin Deficiency Rescued by Tubastatin A., PMID:37268847
A New Mouse Model of Giant Axonal Neuropathy with Overt Phenotypes and Neurodegeneration Driven by Neurofilament Disorganization., PMID:37137704
An induced pluripotent stem cell-based model identifies molecular targets of vincristine neurotoxicity., PMID:36518084
Exploring the neurogenic differentiation of human dental pulp stem cells., PMID:36331951
The 2022 Lady Estelle Wolfson lectureship on neurofilaments., PMID:35950263
Multiple roles for the cytoskeleton in ALS., PMID:35714755
Short amplicon reverse transcription-polymerase chain reaction detects aberrant splicing in genes with low expression in blood missed by ribonucleic acid sequencing analysis for clinical diagnosis., PMID:35476365
Synthesis of a new bifunctional NODA for bioconjugation with PSMA ligand and one-step Al18F labeling., PMID:35278818
Neurofilament Proteins as Biomarkers to Monitor Neurological Diseases and the Efficacy of Therapies., PMID:34646114
Evaluation of peripherin in biofluids of patients with motor neuron diseases., PMID:34264016
Developmental Changes in Peripherin-eGFP Expression in Spiral Ganglion Neurons., PMID:34211371
Enterovirus-A71 exploits peripherin and Rac1 to invade the central nervous system., PMID:33871166
Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients., PMID:33833937
Peripheral pigmented lesions in ABCA4-associated retinopathy., PMID:33706644
Changes in the Gene Expression Profiles of the Inferior Colliculus Following Unilateral Cochlear Ablation in Adult Rats., PMID:33515340
Targeted next-generation sequencing study in familial ALS-FTD Portuguese patients negative for C9orf72 HRE., PMID:32638105
Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation., PMID:32326241
Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway., PMID:32107410
Effect of rice protein hydrolysates on the short-term and long-term retrogradation of wheat starch., PMID:31726166
Molecular signatures of retinal ganglion cells revealed through single cell profiling., PMID:31673015
Shrinkage of the myenteric neurons of the small intestine in patients with multiple system atrophy., PMID:31476714
Evaluating the Effects of Platelet-Rich Plasma and Amniotic Viscous Fluid on Inflammatory Markers in a Human Coculture Model for Osteoarthritis., PMID:31395181
A PRPH splice-donor variant associates with reduced sural nerve amplitude and risk of peripheral neuropathy., PMID:30992453
Recessive pediatric-onset cone-rod dysfunction or dominant maculopathy in a consanguineous family harboring the peripherin mutation p.Arg220Gln., PMID:30822235
MiR-105 and miR-9 regulate the mRNA stability of neuronal intermediate filaments. Implications for the pathogenesis of amyotrophic lateral sclerosis (ALS)., PMID:30385300
Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases., PMID:30228356
Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc., PMID:30150762
Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin., PMID:29196434
An Immortalized Human Dorsal Root Ganglion Cell Line Provides a Novel Context To Study Herpes Simplex Virus 1 Latency and Reactivation., PMID:28404842
Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B', as an Autoantibody Marker in Crohn's Disease using an Immunoproteomics Approach., PMID:28204086
Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea., PMID:28118374
Identification of KRT16 as a target of an autoantibody response in complex regional pain syndrome., PMID:27773721
Type II Cochlear Ganglion Neurons Do Not Drive the Olivocochlear Reflex: Re-Examination of the Cochlear Phenotype in Peripherin Knock-Out Mice., PMID:27570826
Discovery of Phosphorylated Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus., PMID:27185639
Nociceptin/orphanin FQ receptor expression in clinical pain disorders and functional effects in cultured neurons., PMID:27127846
ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin., PMID:26908600
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns., PMID:26861414
Shared Molecular Mechanisms in Alzheimer's Disease and Amyotrophic Lateral Sclerosis: Neurofilament-Dependent Transport of sAPP, FUS, TDP-43 and SOD1, with Endoplasmic Reticulum-Like Tubules., PMID:26605911
hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature., PMID:26004631
Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin., PMID:25398950
Development of the innervation of the human inner ear., PMID:25363666
Quantitative analysis of afferents expressing substance P, calcitonin gene-related peptide, isolectin B4, neurofilament 200, and Peripherin in the sensory root of the rat trigeminal ganglion., PMID:25185935
The Y141C knockin mutation in RDS leads to complex phenotypes in the mouse., PMID:25001182
ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress., PMID:24907400
In vivo detection of peripherin-specific autoreactive B cells during type 1 diabetes pathogenesis., PMID:24610011
Specification of functional cranial placode derivatives from human pluripotent stem cells., PMID:24290755
For research use only. Not for human or drug use.
