Virus-mediated delivery of single-chain antibody targeting TDP-43 protects against neuropathology, cognitive impairment and motor deficit caused by chronic cerebral hypoperfusion., PMID:39778789
Co-pathologies modify hippocampal protein accumulation patterns in neurodegenerative diseases., PMID:39711489
Neuropathological spectrum of anti-IgLON5 disease and stages of brainstem tau pathology: updated neuropathological research criteria of the disease-related tauopathy., PMID:39400557
Vulnerability of neurofilament-expressing neurons in frontotemporal dementia., PMID:39369804
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD., PMID:39363348
Neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases., PMID:39160362
High-sensitivity in situ capture of endogenous RNA-protein interactions in fixed cells and primary tissues., PMID:39152130
Morphometric analysis of spinal motor neuron degeneration in sporadic amyotrophic lateral sclerosis., PMID:39146882
A patient-derived amyotrophic lateral sclerosis blood-brain barrier model for focused ultrasound-mediated anti-TDP-43 antibody delivery., PMID:39138578
Production and characterization of novel monoclonal antibodies against pathological human TDP-43 proteins., PMID:38728009
Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1., PMID:38522514
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia., PMID:38232138
Colocalization of TDP-43 and stress granules at the early stage of TDP-43 aggregation in amyotrophic lateral sclerosis., PMID:37793650
Low T-cell reactivity to TDP-43 peptides in ALS., PMID:37545536
The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence., PMID:37359785
Integrated tandem affinity protein purification using the polyhistidine plus extra 4 amino acids (HiP4) tag system., PMID:36807525
Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage., PMID:36007056
Evidence of cerebellar TDP-43 loss of function in FTLD-TDP., PMID:35879741
Gene Therapy in Amyotrophic Lateral Sclerosis., PMID:35805149
A C-Terminally Truncated TDP-43 Splice Isoform Exhibits Neuronal Specific Cytoplasmic Aggregation and Contributes to TDP-43 Pathology in ALS., PMID:35801182
Age-dependent formation of TMEM106B amyloid filaments in human brains., PMID:35344985
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43., PMID:35264561
TDP-43 and HERV-K Envelope-Specific Immunogenic Epitopes Are Recognized in ALS Patients., PMID:34835107
Aptamer-based enrichment of TDP-43 from human cells and tissues with quantification by HPLC-MS/MS., PMID:34469713
Phosphorylated TAR DNA-binding protein-43: Aggregation and antibody-based inhibition., PMID:34339840
[A case of facial-onset sensory and motor neuronopathy (FOSMN) with cerebellar ataxia and abnormal decrement in repetitive nerve stimulation test]., PMID:33504750
Serum naturally occurring anti-TDP-43 auto-antibodies are increased in amyotrophic lateral sclerosis., PMID:33479441
TDP-43-specific Autoantibody Decline in Patients With Amyotrophic Lateral Sclerosis., PMID:33361387
PCBP2 Is Downregulated in Degenerating Neurons and Rarely Observed in TDP-43-Positive Inclusions in Sporadic Amyotrophic Lateral Sclerosis., PMID:33313661
Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP., PMID:33300249
TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia., PMID:33065281
Monoclonal full-length antibody against TAR DNA binding protein 43 reduces related proteinopathy in neurons., PMID:33021970
Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation., PMID:32992901
Novel monoclonal antibodies targeting the RRM2 domain of human TDP-43 protein., PMID:32905837
Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants., PMID:32887544
Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD-TDP subtypes., PMID:32778941
Disposable immunoplatforms for the simultaneous determination of biomarkers for neurodegenerative disorders using poly(amidoamine) dendrimer/gold nanoparticle nanocomposite., PMID:32474723
Distinct molecular patterns of TDP-43 pathology in Alzheimer's disease: relationship with clinical phenotypes., PMID:32349792
Development of disease-modifying drugs for frontotemporal dementia spectrum disorders., PMID:32203398
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD., PMID:32175624
Use of Capillary Electrophoresis Immunoassay to Search for Potential Biomarkers of Amyotrophic Lateral Sclerosis in Human Platelets., PMID:32090995
TDP-43 aggregation inside micronuclei reveals a potential mechanism for protein inclusion formation in ALS., PMID:31882736
Autophagy Is a Common Degradation Pathway for Bunina Bodies and TDP-43 Inclusions in Amyotrophic Lateral Sclerosis., PMID:31504678
Muscle pathology of hereditary motor and sensory neuropathy with proximal dominant involvement with TFG mutation., PMID:31449671
Improved detection of prostate cancer using a magneto-nanosensor assay for serum circulating autoantibodies., PMID:31404106
C-terminal and full length TDP-43 specie differ according to FTLD-TDP lesion type but not genetic mutation., PMID:31266542
Tau and TDP-43 accumulation of the basal nucleus of Meynert in individuals with cerebral lobar infarcts or hemorrhage., PMID:30922392
Morphology and Distribution of TDP-43 Pre-inclusions in Primary Progressive Aphasia., PMID:30753613
Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers., PMID:30075745
Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals., PMID:29662239
For research use only. Not for human or drug use.
