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Anti-Vaccinia A27 Antibody (8E3#)

Catalog #:   RVV14106 Specific References (47) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: ELISA, FCM, WB
Expression system: Mammalian Cells
Overview

Catalog No.

RVV14106

Expression system

Mammalian Cells

Species reactivity

Vaccinia

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Protein A27, VACWR150, A27L

Concentration

2.65 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P11258

Applications

ELISA, FCM, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

8E3#

Data Image
References

Preparation and application evaluation of monoclonal antibodies against Monkeypox virus A29 protein., PMID:39959162

Assessment of MpoxPlex, a high-throughput and multiplexed immunoassay: a diagnostic accuracy study., PMID:39832516

Different immunogens and prime-boost vaccination strategies affect the efficacy of recombinant candidate vaccines against pathogenic orthopoxviruses., PMID:39511612

A Quadrivalent mRNA Immunization Elicits Potent Immune Responses against Multiple Orthopoxviral Antigens and Neutralization of Monkeypox Virus in Rodent Models., PMID:38675767

Neutralization Determinants on Poxviruses., PMID:38140637

Selective Single-Molecule Nanopore Detection of mpox A29 Protein Directly in Biofluids., PMID:38051760

Serosurvey of Immunity to Monkeypox (Mpox) Virus Antigens in People Living with HIV in South Florida., PMID:38003819

Determination of seroprevalence and kinetics of humoral response using mpox virus A29 protein., PMID:37993690

Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals., PMID:37741831

Mpox virus mRNA-lipid nanoparticle vaccine candidates evoke antibody responses and drive protection against the Vaccinia virus challenge in mice., PMID:37429529

Gold-based paper for antigen detection of monkeypox virus., PMID:36722989

A Nucleic Acid-Based Orthopoxvirus Vaccine Targeting the Vaccinia Virus L1, A27, B5, and A33 Proteins Protects Rabbits against Lethal Rabbitpox Virus Aerosol Challenge., PMID:34851148

Long-term outcomes in patients with advanced melanoma who had initial stable disease with pembrolizumab in KEYNOTE-001 and KEYNOTE-006., PMID:34571336

Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice challenged with vaccinia virus., PMID:32741672

Enhancement of Immune Responses by Guanosine-Based Particles in DNA Plasmid Formulations against Infectious Diseases., PMID:31240233

Species-Specific Conservation of Linear Antigenic Sites on Vaccinia Virus A27 Protein Homologs of Orthopoxviruses., PMID:31146446

Vaccination with a codon-optimized A27L-containing plasmid decreases virus replication and dissemination after vaccinia virus challenge., PMID:28629922

A Prime/Boost PfCS14KM/MVA-sPfCSM Vaccination Protocol Generates Robust CD8+ T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria., PMID:28298290

Antibody Recognition of Immunodominant Vaccinia Virus Envelope Proteins., PMID:28271474

Protection of mice against the highly pathogenic VVIHD-J by DNA and fowlpox recombinant vaccines, administered by electroporation and intranasal routes, correlates with serum neutralizing activity., PMID:27637905

Recombinant Sheep Pox Virus Proteins Elicit Neutralizing Antibodies., PMID:27338444

Development of a Genus-Specific Antigen Capture ELISA for Orthopoxviruses - Target Selection and Optimized Screening., PMID:26930499

Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox., PMID:26889021

A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen., PMID:26208356

Immunomodulator-based enhancement of anti smallpox immune responses., PMID:25875833

A highly specific monoclonal antibody against monkeypox virus detects the heparin binding domain of A27., PMID:25108113

Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in L1 protein., PMID:25031354

L1R, A27L, A33R and B5R vaccinia virus genes expressed by fowlpox recombinants as putative novel orthopoxvirus vaccines., PMID:23578094

Side-by-side comparison of gene-based smallpox vaccine with MVA in nonhuman primates., PMID:22860117

Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease., PMID:21933385

Serological responses in humans to the smallpox vaccine LC16m8., PMID:21715598

Evaluating the orthopoxvirus type I interferon-binding molecule as a vaccine target in the vaccinia virus intranasal murine challenge model., PMID:20844086

A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge., PMID:20659519

Recombinant A27 protein synergizes with modified vaccinia Ankara in conferring protection against a lethal vaccinia virus challenge., PMID:19887133

Immunogenicity and protective efficacy of Semliki forest virus replicon-based DNA vaccines encoding goatpox virus structural proteins., PMID:19559453

Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans., PMID:19162289

Vaccinia virus strain NYVAC induces substantially lower and qualitatively different human antibody responses compared with strains Lister and Dryvax., PMID:19008384

Disparity between levels of in vitro neutralization of vaccinia virus by antibody to the A27 protein and protection of mice against intranasal challenge., PMID:18524827

Heterogeneity in the A33 protein impacts the cross-protective efficacy of a candidate smallpox DNA vaccine., PMID:18482742

Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine., PMID:18234801

Specific tumor cell targeting by a recombinant MVA expressing a functional single chain antibody on the surface of intracellular mature virus (IMV) particles., PMID:18158739

Antibodies to the A27 protein of vaccinia virus neutralize and protect against infection but represent a minor component of Dryvax vaccine--induced immunity., PMID:17763325

Antibody responses to vaccinia membrane proteins after smallpox vaccination., PMID:17570109

Vaccination with Venezuelan equine encephalitis replicons encoding cowpox virus structural proteins protects mice from intranasal cowpox virus challenge., PMID:17292434

Quantification of antibody responses against multiple antigens of the two infectious forms of Vaccinia virus provides a benchmark for smallpox vaccination., PMID:17086190

Human T-cell responses to vaccinia virus envelope proteins., PMID:17005679

Immunogenicity and protection efficacy of monovalent and polyvalent poxvirus vaccines that include the D8 antigen., PMID:16919703

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Vaccinia A27 Antibody (8E3#) [RVV14106]
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